The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
- Author
- BAIGENT, Colin1 ; LANDRAY, Martin J1 ; NEAL, Bruce4 5 ; LIXIN JIANG7 ; LAI SEONG HOOI8 ; LEVIN, Adeera9 ; AGODOA, Lawrence10 ; GAZIANO, Mike11 ; KASISKE, Bertram12 ; WALKER, Robert13 ; MASSY, Ziad A14 ; FELDT-RASMUSSEN, Bo15 ; REITH, Christina1 ; KRAIRITTICHAI, Udom16 ; OPHASCHAROENSUK, Vuddidhej17 ; FELLSTRÖM, Bengt18 ; HOLDAAS, Hallvard19 ; TESAR, Vladimir20 ; WIECEK, Andrzej21 ; GROBBEE, Diederick22 ; DEZEEUW, Dick23 ; GRÖNHAGEN-RISKA, Carola24 ; DASGUPTA, Tanaji25 ; EMBERSON, Jonathan1 ; LEWIS, David1 ; HERRINGTON, William1 ; MAFHAM, Marion1 ; MAJONI, William; WALLENDSZUS, Karl1 ; GRIMM, Richard; PEDERSEN, Terje; TOBERT, Jonathan; ARMITAGE, Jane1 ; BAXTER, Alex1 ; WHEELER, David C2 ; BRAY, Christopher1 ; YIPING CHEN1 ; ZHENGMING CHEN1 ; HILL, Michael1 ; KNOTT, Carol1 ; PARISH, Sarah1 ; SIMPSON, David1 ; SLEIGHT, Peter; YOUNG, Alan1 ; COLLINS, Rory1 ; TOMSON, Charles3 ; WANNER, Christoph3 ; KRANE, Vera3 ; CASS, Alan4 5 ; CRAIG, Jonathan6
[1] Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, United Kingdom
[2] University College London, London, United Kingdom
[3] North Bristol NHSTrust, Bristol, United Kingdom
[4] Department of Medicine 1, Division of Nephrology, University of Wuerzburg, Wuerzburg, Germany
[5] George Institute for Global Health, University of Sydney, Sydney, NSW, Australia
[6] Sydney School of Public Health, Children's Hospital at Westmead, University of Sydney, Sydney, NSW, Australia
[7] China Oxford Centre for International Health Research, Fuwai Hospital, Beijing, Chinese Academy of Medical Sciences and Peking Union Medical College, China
[8] Department of Medicine and Haemodialysis Unit, Sultanah Aminah Hospital, Johor Bahru, Malaysia
[9] University of British Columbia, Vancouver, BC, Canada
[10] National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States
[11] Harvard Medical School, VA Boston, Brigham and Women's Hospital, Boston, MA, United States
[12] University of Minnesota, Minneapolis, MN, United States
[13] Dunedin School of Medicine, University of Otago, Otago, New Zealand
[14] Division of Clinical Pharmacology and Division of Nephrology, Amiens University Hospital, and INSERM ERI-12, University of Picardie Jules Verne, Amiens, France
[15] Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
[16] Division of Nephrology, Department of Medicine, Rajavithi Hospital, Bangkok, Thailand
[17] Renal Division, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
[18] University Hospital, Uppsala, Sweden
[19] Renal Section, Department of Organ Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway
[20] Department of Nephrology, First School of Medicine and General University Hospital, Charles University, Prague, Czech Republic
[21] Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland
[22] Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands
[23] Department of Clinical Pharmacology, University Medical CenterGroningen, Groningen, Netherlands
[24] Helsinki University Hospital, Helsinki, Finland
[25] Oxford Radcliffe Hospitals NHSTrust, Oxford, United Kingdom
SHARP Investigators - Source
Lancet (British edition). 2011, Vol 377, Num 9784, pp 2181-2192, 12 p ; ref : 26 ref
- CODEN
- LANCAO
- ISSN
- 0140-6736
- Scientific domain
- General medicine general surgery
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Association médicamenteuse Cholestérol LDL Coeur Essai clinique Ezétimibe Homme Hypocholestérolémiant Hypolipémiant Malade Médecine Néphropathie chronique Placebo Protection Rein Simvastatine Essai randomisé contrôlé Appareil circulatoire Appareil urinaire Dérivé de la statine Enzyme Hydroxymethylglutaryl-CoA reductase Inhibiteur de l'HMG-CoA reductase Inhibiteur enzyme Insuffisance rénale Oxidoreductases Pathologie de l'appareil urinaire Pathologie du rein
- Keyword (en)
- Drug combination Cholesterol LDL Heart Clinical trial Ezetimibe Human Hypocholesterolemic agent Antilipemic agent Patient Medicine Chronic kidney disease Placebo Protection Kidney Simvastatin Randomized controlled trial Circulatory system Urinary system Statin derivative Enzyme Hydroxymethylglutaryl-CoA reductase HMG-CoA reductase inhibitor Enzyme inhibitor Renal failure Oxidoreductases Urinary system disease Kidney disease
- Keyword (es)
- Asociación medicamentosa Colesterol LDL Corazón Ensayo clínico Ezetimiba Hombre Hipocolesterolemiante Hipolipemiante Enfermo Medicina Nefropatía crónica Placebo Protección Riñón Simvastatina Ensayo aleatorio controlado Aparato circulatorio Aparato urinario Statina derivado Enzima Hydroxymethylglutaryl-CoA reductase Inhibidor HMG-CoA reductase Inhibidor enzima Insuficiencia renal Oxidoreductases Aparato urinario patología Riñón patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14A Nephropathies. Renovascular diseases. Renal failure / 002B14A05 Renal failure
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14E Urinary system involvement in other diseases. Miscellaneous / 002B14E01 Kidneys
- Discipline
- Generalities in medical sciences Nephrology. Urinary tract diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24333464
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0140-6736(11)60739-3 
https://dx.doi.org/10.1016/S0140-6736(11)60739-3
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arXiv access
