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Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults

Author
SALAVERRIA, Itziar1 ; PHILIPP, Claudia2 ; BERGER, Hilmar5 ; FEY, Miriam1 ; HARDER, Lana1 ; HASENCLEVER, Dirk5 ; HUMMEL, Michael9 ; LOEFFLER, Markus5 ; MAHN, Friederike1 ; MARTIN-GUERRERO, Idoia1 ; PELLISSERY, Shoji1 ; POTT, Christiane7 ; OSCHLIES, Ilske3 ; PFREUNDSCHUH, Michael10 ; REITER, Alfred6 ; RICHTER, Julia1 ; ROSOLOWSKI, Maciej5 ; SCHWAENEN, Carsten11 ; STEIN, Harald9 ; TRÜMPER, Lorenz12 ; WESSENDORF, Swen11 ; SPANG, Rainer4 ; KÜPPERS, Ralf2 ; KOHLER, Christian W4 ; KLAPPER, Wolfram3 ; SIEBERT, Reiner1 ; KREUZ, Markus5 ; SZCZEPANOWSKI, Monika3 ; BURKHARDT, Birgit6 ; TRAUTMANN, Heiko7 ; GESK, Stefan1 ; ANDRUSIEWICZ, Miroslaw1 8
[1] Institute of Human Genetics, University Hospital Schleswig-Holstein Campus Kiel/Christian-Albrechts University Kiel, Kiel, Germany
[2] Institute of Cell Biology (Cancer Research), Medical School, University of Duisburg-Essen, Essen, Germany
[3] Department of Pathology, Hematopathology Section and Lymph Node, University Hospital Schleswig-Holstein Campus Kiel/Christian-Albrechts University Kiel, Kiel, Germany
[4] Institute of Functional Genomics, University of Regensburg, Regensburg, Germany
[5] Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany
[6] Department of Pediatric Hematology and Oncology, Justus-Liebig University, Giessen, Germany
[7] Second Medical Department, University Hospital Schleswig-Holstein Campus Kiel/Christian-Albrechts University Kiel, Kiel, Germany
[8] Department of Cell Biology, University of Medical Sciences, Poznan, Poland
[9] Institute of Pathology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Berlin, Germany
[10] Department of Internal Medicine I, University of Saarland, Homburg, Germany
[11] Internal Medicine III, University Hospital of Ulm, Ulm, Germany
[12] Department of Hematology and Oncology, Georg-August University of Göttingen, Göttingen, Germany
Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe, the German High-Grade Lymphoma Study Group, and the Berlin-Frankfurt-Münster-NHL trial group, Germany
Source

Blood. 2011, Vol 118, Num 1, pp 139-147, 9 p ; ref : 36 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Adulte jeune Cellule germinale Centre germinatif Cytogénétique Enfant Hématologie Lymphocyte B Lymphome Soustype Translocation chromosomique Facteur de régulation de l'interféron 4 Aberration chromosomique Cancer Chromosome anormal Homme Hémopathie maligne Syndrome lymphoprolifératif
Keyword (en)
Young adult Germinal cell Germinative center Cytogenetics Child Hematology B-Lymphocyte Lymphoma Subtype Chromosome translocation Interferon regulatory factor 4 Chromosomal aberration Cancer Abnormal chromosome Human Malignant hemopathy Lymphoproliferative syndrome
Keyword (es)
Adulto joven Célula germinal Centro germinativo Citogenética Niño Hematología Linfocito B Linfoma Subtipo Translocación cromosómica Aberración cromosómica Cáncer Cromosoma anormal Hombre Hemopatía maligna Linfoproliferativo síndrome
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B23 Medical genetics / 002B23B Chromosome aberrations

Discipline
Blood diseases Medical genetics
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
24336276

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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