Near-fatal tramadol cardiotoxicity in a CYP2D6 ultrarapid metabolizer
- Author
- ELKALIOUBIE, Ahmed1 ; ALLORGE, Delphine2 3 ; ROBRIQUET, Laurent1 4 ; WIART, Jean-François2 ; GARAT, Anne2 3 ; BROLY, Franck2 3 ; FOURRIER, François1 4
[1] Service de Reanimation Polyvalente, Hôpital Roger Salengro, CHRU Lille, Rue Emile Laine, 59037 Lille, France
[2] Laboratoire de Toxicologie & Genopathies, Centre de Biologie-Pathologie, CHRU Lille, Lille, France
[3] EA4483, Faculté de Medecine, UDSL, Univ Lille Nord de France, Lille, France
[4] Departement Universitaire de Reanimation, Faculté de Medecine, UDSL, Univ Lille Nord de France, Lille, France - Source
European journal of clinical pharmacology. 2011, Vol 67, Num 8, pp 855-858, 4 p ; ref : 20 ref
- ISSN
- 0031-6970
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- CYP2D6 Cardiotoxicity Opioids Tramadol Ultra-rapid metabolism
- Keyword (fr)
- Adulte Age 20-29 Analgésique Caucasoïde Cytochrome P450 Effet secondaire Etude cas Femelle Homme Isozyme Métabolisme Opiacés Pathologie de l'appareil circulatoire Peptide opioïde Pharmacovigilance Toxicité Tramadol Cytochrome P4502D6 Enzyme Ethnie Pharmacocinétique
- Keyword (en)
- Adult Age 20-29 Analgesic Caucasoid Cytochrome P450 Secondary effect Case study Female Human Isozyme Metabolism Opiates Cardiovascular disease Opioid peptide Pharmacovigilance Toxicity Tramadol Enzyme Ethnic group Pharmacokinetics
- Keyword (es)
- Adulto Edad 20-29 Analgésico Caucásico Citocromo P450 Efecto secundario Estudio caso Hembra Hombre Isozima Metabolismo Opiados Aparato circulatorio patología Péptido opioide Farmacovigilancia Toxicidad Tramadol Enzima Etnia Farmacocinética
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U03 Toxicity: cardiovascular system
- Discipline
- Drugs toxicity and drug intoxications Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24344112
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00228-011-1080-x 
https://dx.doi.org/10.1007/s00228-011-1080-x
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