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Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins

Author
LEE, Kyung-Hun1 ; LEE, Ju-Hee2 ; HAN, Sae-Won1 2 ; IM, Seock-Ah1 2 ; KIM, Tae-You1 2 3 ; OH, Do-Youn1 2 ; BANG, Yung-Jue1 2 3
[1] Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of
[2] Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea, Republic of
[3] Department of Molecular Medicine and Biopharmaceutical Sciences, WCU, Seoul National University, Seoul, Korea, Republic of
Source

Cancer science. 2011, Vol 102, Num 7, pp 1388-1395, 8 p ; ref : 35 ref

ISSN
1347-9032
Scientific domain
Medical oncology
Publisher
Blackwell, Richmond
Publication country
Australia
Document type
Article
Language
English
Keyword (fr)
Activité biologique Anticancéreux Cancer de l'estomac Cancérologie Cellule tumorale Dégradation Homme Inhibiteur Multicatalytic endopeptidase complex Protéine choc thermique Protéine de choc thermique 90 Cancer Enzyme Hydrolases Pathologie de l'appareil digestif Pathologie de l'estomac Peptidases Tumeur maligne
Keyword (en)
Biological activity Antineoplastic agent Stomach cancer Cancerology Tumor cell Degradation Human Inhibitor Multicatalytic endopeptidase complex Heat shock protein Heat shock protein 90 Cancer Enzyme Hydrolases Digestive diseases Gastric disease Peptidases Malignant tumor
Keyword (es)
Actividad biológica Anticanceroso Cáncer del estómago Cancerología Célula tumoral Degradación Hombre Inhibidor Multicatalytic endopeptidase complex Proteína choque térmico Proteína de choque térmico 90 Cáncer Enzima Hydrolases Aparato digestivo patología Estómago patología Peptidases Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors

Discipline
Gastroenterology. Liver. Pancreas. Abdomen Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
24362362

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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