Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials
- Author
- HOLMES, Michael V1 ; NEWCOMBE, Paul6 7 ; SMEETH, Liam6 ; FOWKES, F. Gerald R15 ; ALGRA, Ale16 18 ; SHMELEVA, Veronika17 ; SZOLNOKI, Zoltan; ROEST, Mark19 ; LINNEBANK, Michael20 ; ZACHO, Jeppe21 ; NALLS, Michael A22 ; SINGLETON, Andrew B22 ; HUBACEK, Jaroslav A8 ; FERRUCCI, Luigi; HARDY, John5 ; WORRALL, Bradford B24 ; RICH, Stephen S25 ; MATARIN, Mar4 ; NORMAN, Paul E; FLICKER, Leon23 ; ALMEIDA, Osvaldo P; VAN BOCKXMEER, Frank M; SHIMOKATA, Hiroshi; SOFAT, Reecha2 ; KHAW, Kay-Tee; WAREHAM, Nicholas J; BOBAK, Martin1 ; STERNE, Jonathan A. C; SMITH, George Davey; TALMUD, Philippa J3 6 ; DUIJN, Cornelia Van11 ; HUMPHRIES, Steve E3 6 ; PRICE, Jackie F15 ; EBRAHIM, Shah6 ; RICKETTS, Sally L; LAWLOR, Debbie A; HANKEY, Graeme J; MESCHIA, James F; SANDHU, Manjinder S10 9 ; HINGORANI, Aroon D1 2 ; CASAS, Juan P1 ; COOPER, Jackie3 ; BRETELER, Monique M. B11 12 ; BAUTISTA, Leonelo E13 ; SHARMA, Pankaj14 ; WHITTAKER, John C7
[1] Department of Epidemiology and Public Health, University College London, London, United Kingdom
[2] Department of Clinical Pharmacology, University College London, London, United Kingdom
[3] Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom
[4] Department of Clinical and Experimental Epilepsy, University College London, London, United Kingdom
[5] Institute of Neurology, University College London, London, United Kingdom
[6] Facultyof Epidemiology and Public Health, London School of Hygiene andTropical Medicine, London, United Kingdom
[7] Genetics, R&D, GlaxoSmithKline, Stevenage, United Kingdom
[8] Institute for Clinical and Experimental Medicine and Centre for Cardiovascular Research, Prague, Czech Republic
[9] Department of Public Health and Primary Care (M S Sandhu PhD), University ofCambridge, Cambridge, United Kingdom
[10] Genetic Epidemiology Group, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
[11] Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, Netherlands
[12] German Centre for Neurodegenerative diseases, Bonn, Germany
[13] Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin at Madison, Madison, WI, United States
[14] Imperial College Cerebrovascular Research Unit (ICCRU), Imperial College London, London, United Kingdom
[15] Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
[16] Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
[17] Russian Institute of Haematology and Transfusion, St Petersburg, Russian Federation
[18] Utrecht Stroke Center, Department of Neurology, University Medical Center Utrecht, Netherlands
[19] Depa rtment of Clinical Chemistry and Haematology, University Medical Center Utrecht, Netherlands
[20] Department of Neurology, University Hospital Zurich, Zurich, Switzerland
[21] Department of Clinical Biochemistry, Herlev University Hospital, Herlev, Denmark
[22] Laboratory of Neurogenetics, National Institute on Aging, US National Institute of Health, Bethesda, MD, United States
[23] National Institute on Aging, Baltimore, MD, United States
[24] Department of Neurology, University of Virginia, Charlottesville, VA, United States
[25] Center for Public Health Genomics, University of Virginia, Charlottesville, VA, United States - Source
Lancet (British edition). 2011, Vol 378, Num 9791, pp 584-594, 11 p ; ref : 62 ref
- CODEN
- LANCAO
- ISSN
- 0140-6736
- Scientific domain
- General medicine general surgery
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- Russian
- Keyword (fr)
- Accident cérébrovasculaire Acide folique Aliment Alimentation Analyse risque Association Folate Génotype Homme Homocystéine Methylenetetrahydrofolate reductase (NADPH) Modification Métaanalyse Nutrition Population Régime alimentaire Traitement diététique Typage Vitamine Aminoacide soufré Enzyme Oxidoreductases Pathologie cérébrovasculaire Pathologie de l'appareil circulatoire Pathologie de l'encéphale Pathologie des vaisseaux sanguins Pathologie du système nerveux central Pathologie du système nerveux Thiol
- Keyword (en)
- Stroke Folic acid Food Feeding Risk analysis Association Folate Genotype Human Homocystein Methylenetetrahydrofolate reductase (NADPH) Modification Metaanalysis Nutrition Population Diet Diet therapy Typing Vitamin Sulfur containing aminoacid Enzyme Oxidoreductases Cerebrovascular disease Cardiovascular disease Cerebral disorder Vascular disease Central nervous system disease Nervous system diseases Thiol
- Keyword (es)
- Accidente cerebrovascular Acido fólico Alimento Alimentación Análisis riesgo Asociación Folato Genotipo Hombre Homocisteína Methylenetetrahydrofolate reductase (NADPH) Modificación Meta-análisis Nutrición Población Régimen alimentario Tratamiento dietético Tipificación Vitamina Aminoácido azufrado Enzima Oxidoreductases Vaso sanguíneo encéfalo patología Aparato circulatorio patología Encéfalo patología Vaso sanguíneo patología Sistema nervosio central patología Sistema nervioso patología Tiol
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B26 Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) / 002B26F Diseases of the digestive system
- Discipline
- Generalities in medical sciences Metabolic diseases Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, speech therapy, crenotherapy. Dietary management and various treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24419488
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0140-6736(11)60872-6 
https://dx.doi.org/10.1016/S0140-6736(11)60872-6
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arXiv access
