Caspase―8 regulates TNF―α―induced epithelial necroptosis and terminal ileitis
- Author
- GÜNTHER, Claudia1 ; MARTINI, Eva1 ; BECKER, Christoph1 ; WITTKOPF, Nadine1 ; AMANN, Kerstin2 ; WEIGMANN, Benno1 ; NEUMANN, Helmut1 ; WALDNER, Maximilian J1 ; HEDRICK, Stephen M3 ; TENZER, Stefan4 ; NEURATH, Markus F1
[1] Department of Medicine 1, Friedrich-Alexander-University, 91054 Erlangen, Germany
[2] Department of Nephropathology, Friedrich-Alexander-University, 91054 Erlangen, Germany
[3] Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California 92093, United States
[4] Institute of Immunology, Johannes Gutenberg University, 55131 Mainz, Germany - Source
Nature (London). 2011, Vol 477, Num 7364, pp 335-339, 5 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Antimicrobien Caspase Cellule Paneth Cellule caliciforme Cellule épithéliale Entérite de Crohn Epithélium Facteur nécrose tumorale α Fonction cellulaire Homme Iléite Iléon Inflammation Intestin Mort cellulaire Mucus Pathogénie Rectocolite ulcérohémorragique Régulation Survie Maladie inflammatoire de l'intestin Enzyme Hydrolases Maladie inflammatoire Pathologie de l'appareil digestif Pathologie de l'intestin Peptidases
- Keyword (en)
- Animal Antimicrobial agent Caspase Paneth cell Goblet cell Epithelial cell Crohn disease Epithelium Tumor necrosis factor α Cell function Human Ileitis Ileum Inflammation Gut Cell death Mucus Pathogenesis Ulcerative colitis Regulation(control) Survival Inflammatory bowel disease Enzyme Hydrolases Inflammatory disease Digestive diseases Intestinal disease Peptidases
- Keyword (es)
- Animal Antimicrobiano Caspase Célula Paneth Célula caliciforme Célula epitelial Enteritis Crohn Epitelio Factor necrosis tumoral α Función celular Hombre Ileitis Ileon Inflamación Intestino Muerte celular Moco Patogenia Rectocolitis ulcerohemorrágica Regulación Sobrevivencia Enfermedad inflamatoria intestinal Enzima Hydrolases Enfermedad inflamatoria Aparato digestivo patología Intestino patología Peptidases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B03 Other diseases. Semiology
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24500746
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature10400 
https://dx.doi.org/10.1038/nature10400
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