Targeting Heat Shock Proteins 70/90 and Proteasome for Cancer Therapy
- Author
- WANG, R. E1
[1] Department of Chemistry, Washington University, St Louis, MO, 63130, United States - Source
Current medicinal chemistry. 2011, Vol 18, Num 27, pp 4250-4264, 15 p ; ref : 142 ref
- ISSN
- 0929-8673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Bentham, Oak Park, IL
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- 26S proteasome Heat shock protein 90 (HSP90) cancer clinical trials heat shock protein 70 (HSP70) proteasomal degradation simultaneous inhibition
- Keyword (fr)
- Activité biologique Anticancéreux Antiviral Bortézomib Chaperon Ciblage Essai clinique Inhibition Molécule petite Peptidases Protéine choc thermique Protéine de choc thermique 90 Ritonavir Traitement Transduction signal Tumeur maligne Proteasome endopeptidase complex Protéine Hsp70 Bore Composé organique Cancer Enzyme Hydrolases Inhibiteur enzyme Inhibiteur protease
- Keyword (en)
- Biological activity Antineoplastic agent Antiviral Bortezomib Chaperone Targeting Clinical trial Inhibition Small molecule Peptidases Heat shock protein Heat shock protein 90 Ritonavir Treatment Signal transduction Malignant tumor Proteasome endopeptidase complex Boron Organic compounds Cancer Enzyme Hydrolases Enzyme inhibitor Protease inhibitor
- Keyword (es)
- Actividad biológica Anticanceroso Antiviral Bortezomib Chaperone Blancado Ensayo clínico Inhibición Molécula pequeña Peptidases Proteína choque térmico Proteína de choque térmico 90 Ritonavir Tratamiento Transducción señal Tumor maligno Proteasome endopeptidase complex Boro Compuesto orgánico Cáncer Enzima Hydrolases Inhibidor enzima Inhibidor proteasa
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24549624
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2174/092986711797189574 
https://dx.doi.org/10.2174/092986711797189574
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