Population PK and IgE Pharmacodynamic Analysis of a Fully Human Monoclonal Antibody Against IL4 Receptor
- Author
- KAKKAR, Tarundeep1 ; SUNG, Cynthia2 ; STARCEVIC, Martha6 ; PEIMING MA1 ; GIBIANSKY, Leonid3 ; VU, Thuy1 ; NARAYANAN, Adimoolam1 ; LIN, Shao-Lee4 ; VINCENT, Michael5 ; BANFIELD, Christopher5 ; COLBERT, Alex1 ; HOOFRING, Sarah6
[1] Department of Pharmacokinetics and Metabolism, Amgen Inc., Thousand Oaks, California 9I320, United States
[2] Rainbow Pharma Consulting, Pte. Ltd, Singapore, Singapore
[3] QuantPharm LLC, North Potomac, Maryland, United States
[4] Department of General Medicine & Inflammation, Amgen Inc, Thousand Oaks, California 91320, United States
[5] Department of Early Development, Amgen Inc, Thousand Oaks, California 91320, United States
[6] Department of Clinical Immunology & BSM, Amgen Inc, Thousand Oaks, California 91320, United States - Source
Pharmaceutical research. 2011, Vol 28, Num 10, pp 2530-2542, 13 p ; ref : 30 ref
- CODEN
- PHREEB
- ISSN
- 0724-8741
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- IL-4Rα asthma monoclonal antibody pharmacodynamics pharmacokinetics
- Keyword (fr)
- Activité biologique Anticorps monoclonal Asthme Homme IgE Pharmacocinétique Récepteur biologique Technologie pharmaceutique Bronchopneumopathie obstructive Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons
- Keyword (en)
- Biological activity Monoclonal antibody Asthma Human IgE Pharmacokinetics Biological receptor Pharmaceutical technology Obstructive pulmonary disease Respiratory disease Bronchus disease Lung disease
- Keyword (es)
- Actividad biológica Anticuerpo monoclonal Asma Hombre IgE Farmacocinética Receptor biológico Tecnología farmacéutica Enfermedad pulmonar obstructiva Aparato respiratorio patología Bronquio patología Pulmón patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24618381
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s11095-011-0481-y 
https://dx.doi.org/10.1007/s11095-011-0481-y
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