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Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Author
CHAMBERS, John C1 2 3 ; WEIHUA ZHANG1 3 ; COIN, Lachlan J1 ; GUOHONG DENG13 ; GIEGER, Christian14 ; HEARD-COSTA, Nancy L15 ; HOTTENGA, Jouke-Jan16 ; KÜHNELL, Brigitte4 ; KUMAR, Vinod17 ; LAGOU, Vasiliki18 19 20 ; LIMING LIANG21 22 ; LUAN, Jian'an23 ; SEHMI, Joban3 4 ; VIDAL, Pedro Marques24 ; LEACH, Irene Mateo7 ; O'REILLY, Paul F1 ; PEDEN, John F25 ; RAHMIOGLU, Nilufer19 ; SOININEN, Pasi; SPELIOTES, Elizabeth K; XIN YUAN; THORLEIFSSON, Gudmar8 ; ALIZADEH, Behrooz Z18 ; XINZHONG LI5 ; ATWOOD, Larry D; BORECKI, Ingrid B; BROWN, Morris J; CHAROEN, Pimphen1 ; CUCCA, Francesco9 ; DAS, Debashish3 ; DE GEUS, Eco J. C16 ; DIXON, Anna L; DÖRING, Angela; EHRET, Georg; WASS, Mark N6 ; EYJOLFSSON, Gudmundur I; FARRALL, Martin25 ; FOROUHI, Nita G23 ; FRIEDRICH, Nele; GOESSLING, Wolfram; GUDBJARTSSON, Daniel F8 ; HARRIS, Tamara B; HARTIKAINEN, Anna-Liisa; HEATH, Simon; HIRSCHFIELD, Gideon M; VAN DER HARST, Pim7 ; HOFMAN, Albert10 11 ; HOMUTH, Georg; HYPPÖNEN, Elina; JANSSEN, Harry L. A10 ; JOHNSON, Toby; KANGAS, Antti J; KEMA, Ido P; HOLM, Hilma8 ; SANNA, Serena9 ; KAVOUSI, Maryam10 11 ; BAUMEISTER, Sebastian E12
[1] Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, United Kingdom
[2] Imperial College Healthcare National Health Service (NHS) Trust, London, United Kingdom
[3] Ealing Hospital NHS Trust, Middlesex, United Kingdom
[4] National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, United Kingdom
[5] Institute of Clinical Science, Imperial College London, Royal Brompton Hospital, London, United Kingdom
[6] Structural Bioinformatics Group, Division of Molecular Biosciences, Imperial College London, South Kensington, London, United Kingdom
[7] Department of Cardiology, University Medical Center Groningen, University of Groningen, Netherlands
[8] CODE genetics, Reykjavik, Iceland
[9] Istituto di Ricerca Genetica e Biomedica del Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy
[10] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands
[11] Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Health Aging, Rotterdam, Netherlands
[12] Institute for Community Medicine, University of Greifswald, Germany
[13] Institute of Infectious Diseases, Southwest Hospital, Third Military Medical University, Chongqing, China
[14] Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
[15] Department of Neurology, Boston University School of Medicine, Boston Massachusetts, United States
[16] Department of Biological Psychology, VU University Amsterdam (VUA), Amsterdam, Netherlands
[17] Laboratory of Molecular Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
[18] Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
[19] Wellcome Trust Center for Human Genetics, University of Oxford, Oxford, United Kingdom
[20] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom
[21] Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States
[22] Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States
[23] Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom
[24] Institute of Social and Preventive Medicine (IUMSP), University Hospital and University of Lausanne, Lausanne, Switzerland
[25] Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
COMPETING FINANCIAL INTERESTS
Source

Nature genetics. 2011, Vol 43, Num 11, pp 1131-1138, 8 p ; ref : 47 ref

CODEN
NGENEC
ISSN
1061-4036
Scientific domain
Genetics
Publisher
Nature Publishing Group, New York, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Association Concentration Enzyme Foie Identification Locus Plasma Echelle du génome Appareil digestif
Keyword (en)
Association Concentration Enzyme Liver Identification Locus Plasma Digestive system
Keyword (es)
Asociación Concentración Enzima Hígado Identificación Locus Plasma Aparato digestivo
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution

Discipline
Eukaryotes genetics. Biological and molecular evolution
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
24750154

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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