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A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging

Author
LEE, Eunsung1 ; KAMLET, Adam S1 ; POWERS, David C1 ; NEUMANN, Constanze N1 ; BOURSALIAN, Gregory B1 ; FURUYA, Takeru1 ; CHOI, Daniel C1 ; HOOKER, Jacob M2 3 ; RITTER, Tobias1 3
[1] Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, United States
[2] Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, United States
[3] Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, United States
Source

Science (Washington, D.C.). 2011, Vol 334, Num 6056, pp 639-642, 4 p ; ref : 31 ref

CODEN
SCIEAS
ISSN
0036-8075
Scientific domain
Multidisciplinary
Publisher
American Association for the Advancement of Science, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Composé aromatique Composé marqué Electrophile Enrichissement isotopique Fluor 18 Fluor Isotope Fluor composé organique Fluoration Fluorure Imagerie médicale Isotope du fluor Palladium Réactif chimique Réaction nucléophile Synthèse chimique Tomographie par émission de positons Métal transition Platinoïde
Keyword (en)
Aromatic compound Labelled compound Electrophile Isotope enrichment Fluorine 18 Fluorine Isotopes Organic fluorine compounds Fluorination Fluorides Medical imagery Fluorine isotopes Palladium Chemical reagent Nucleophilic reaction Chemical synthesis Positron emission tomography Transition metal Platinoid
Keyword (es)
Compuesto aromático Compuesto marcado Electrófilo Enriquecimiento isotópico Fluor Isótopo Fluoración Fluoruro Imaginería médica Paladio Reactivo químico Reacción nucléofila Síntesis química Tomografía emisión positrones Metal transición Platinoide
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03B Reactivity and mechanisms / 001C03B05 Labelled compounds chemistry

Discipline
Organic chemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
24758558

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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