Functional Links Between Aβ Toxicity, Endocytic Trafficking, and Alzheimer's Disease Risk Factors in Yeast
- Author
- TREUSCH, Sebastian1 2 ; HAMAMICHI, Shusei1 3 ; HAN, Haesun1 ; LINDHAGEN-PERSSON, Malin7 ; REIMAN, Eric M8 9 ; EVANS, Denis A10 ; BENNETT, David A11 ; OLOFSSON, Anders7 ; DEJAGER, Philip L4 5 ; TANZI, Rudolph E6 ; CALDWELL, Kim A3 ; CALDWELL, Guy A3 ; GOODMAN, Jessica L1 ; LINDQUIST, Susan1 2 ; MATLACK, Kent E. S1 2 ; CHUNG, Chee Yeun1 ; BARU, Valeriya1 2 ; SHULMAN, Joshua M4 5 ; PARRADO, Antonio6 ; BEVIS, Brooke J1 ; VALASTYAN, Julie S1 2
[1] Whitehead Institute for Biomedical Research, Cambridge, MA 02142, United States
[2] Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States
[3] Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL 35487, United States
[4] Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States
[5] Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, United States
[6] Genetics and Aging Research Unit, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, United States
[7] Department of Medical Biochemistry and Biophysics, Umea University, Umea, Sweden
[8] Neurogenomics Division, Translational Genomics Research Institute and Arizona Alzheimer's Consortium, Phoenix, AZ 85004, United States
[9] Banner Alzheimer's Institute and Department of Psychiatry, University of Arizona, Phoenix, AZ 85006, United States
[10] Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, United States
[11] Rush Alzheimer's Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, United States - Source
Science (Washington, D.C.). 2011, Vol 334, Num 6060, pp 1241-1245, 5 p ; ref : 43 ref
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Démence d'Alzheimer Endocytose Facteur risque Levure Toxicité
- Keyword (en)
- Alzheimer disease Endocytosis Risk factor Yeast Toxicity
- Keyword (es)
- Demencia Alzheimer Endocitosis Factor riesgo Levadura Toxicidad
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H08 Endocytosis
- Discipline
- Analytical, structural and metabolic biochemistry Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25274322
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1213210 
https://dx.doi.org/10.1126/science.1213210
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