Denosumab and bone-metastasis-free survival in men with @ castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial
- Author
- SMITH, Matthew R1 ; SAAD, Fred2 ; TAMMELA, Teuvo L11 ; EGERDIE, Blair12 ; VAN POPPEL, Hendrik13 ; CHIN, Joseph14 ; MOROTE, Juan15 ; GOMEZ-VEIGA, Francisco16 ; BORKOWSKI, Tomasz17 ; ZHISHEN YE18 ; KUPIC, Amy18 ; DANSEY, Roger18 ; COLEMAN, Robert3 ; GOESSL, Carsten18 ; SHORE, Neal4 ; FIZAZI, Karim5 ; TOMBAL, Bertrand6 ; MILLER, Kurt7 ; SIEBER, Paul8 ; KARSH, Lawrence9 ; DAMIAO, Ronaldo10
[1] Massachusetts General Hospital Cancer Center, Boston, MA, United States
[2] University of Montreal Hospital Center, CRCHUM, Montreal, QC, Canada
[3] Weston Park Hospital, Sheffield, United Kingdom
[4] Carolina Urological Research Center, Myrtle Beach, SC, United States
[5] Institut Gustave Roussy, University of Paris, Sud, Villejuif, France
[6] Université Catholique de Louvain Cliniques Universitaires Saint Luc, Bruxelles, Belgium
[7] Charite Berlin, Berlin, Germany
[8] Urological Associates of Lancaster, Lancaster, PA, United States
[9] The Urology Center of Colorado, Denver, CO, United States
[10] Hospital Universitario Pedro Ernesto, Rio de Janeiro, Brazil
[11] Tampere University Hospital, Tampere, Finland
[12] Urology Associates/Urologic Medical Research, Kitchener, ON, Canada
[13] Universitair Ziekenhuis Gasthuisberg, Leuven, Belgium
[14] London Health Sciences Centre, London, ON, Canada
[15] Hospital Vall d'Hebron, Barcelona, Spain
[16] Complejo Hospitalario Universitario, A Coruña, Spain
[17] Medical University of Warsaw, Szpital Dzieciątka Jezus, Warsaw, Poland
[18] Amgen Inc, Thousand Oaks, CA, United States - Source
Lancet (British edition). 2012, Vol 379, Num 9810, pp 39-46, 8 p ; ref : 30 ref
- CODEN
- LANCAO
- ISSN
- 0140-6736
- Scientific domain
- General medicine general surgery
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adulte Cancer de la prostate Castration Dénosumab Essai clinique phase III Essai clinique Forme libre Homme Immunomodulateur Mâle Médecine Métastase osseuse Placebo Résistance Résultat Survie Essai randomisé contrôlé Anticorps monoclonal Cancer Pathologie de l'appareil génital mâle Pathologie de l'appareil urinaire Pathologie de la prostate Pathologie du système ostéoarticulaire Tumeur maligne
- Keyword (en)
- Adult Prostate cancer Castration Denosumab Phase III trial Clinical trial Free form Human Immunomodulator Male Medicine Bone metastasis Placebo Resistance Result Survival Randomized controlled trial Monoclonal antibody Cancer Male genital diseases Urinary system disease Prostate disease Diseases of the osteoarticular system Malignant tumor
- Keyword (es)
- Adulto Cáncer de la próstata Castración Denosumab Ensayo clínico fase III Ensayo clínico Forma libre Hombre Inmunomodulador Macho Medicina Metástasis ósea Placebo Resistencia Resultado Sobrevivencia Ensayo aleatorio controlado Anticuerpo monoclonal Cáncer Aparato genital macho patología Aparato urinario patología Prostata patología Sistema osteoarticular patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14D Tumors of the urinary system / 002B14D02 Urinary tract. Prostate gland
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15C Tumors of striated muscle and skeleton
- Discipline
- Generalities in medical sciences Nephrology. Urinary tract diseases Osteoarticular pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25357176
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0140-6736(11)61226-9 
https://dx.doi.org/10.1016/S0140-6736(11)61226-9
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