Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
- Author
- MEISTER, Stephan1 ; PLOUFFE, David M2 ; COHEN, Steve2 ; DHARIA, Neekesh V1 ; GAGARING, Kerstin2 ; GETTAYACAMIN, Montip4 ; GORDON, Perry2 ; GROESSL, Todd2 ; KATO, Nobutaka2 ; LEE, Marcus C. S5 ; MCNAMARA, Case W2 ; FIDOCK, David A5 6 ; KUHEN, Kelli L2 ; NAGLE, Advait; NAM, Tae-Gyu7 ; RICHMOND, Wendy; ROLAND, Jason; ROTTMANN, Matthias8 9 ; BIN ZHOU; FROISSARD, Patrick10 11 ; GLYNNE, Richard J; MAZIER, Dominique10 11 12 ; SATTABONGKOT, Jetsumon13 ; BONAMY, Ghislain M. C2 ; SCHULTZ, Peter G7 ; TUNTLAND, Tove; WALKER, John R; YINGYAO ZHOU; CHATTERJEE, Arnab; DIAGANA, Thierry T14 ; WINZELER, Elizabeth A1 ; TAO WU2 ; WHITNEY BARNES, S2 ; BOPP, Selina E1 ; BORBOA, Rachel2 ; BRIGHT, A. Taylor1 3 ; CHE, Jianwei2
[1] Department of Genetics, The Scripps Research Institute, La Jolla, CA 92037, United States
[2] Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, United States
[3] Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, CA 92093, United States
[4] Department of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok 10400, Thailand
[5] Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, United States
[6] Department of Medicine (Division of Infectious Diseases), Columbia University Medical Center, New York, NY 10032, United States
[7] Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, United States
[8] Parasite Chemotherapy, Swiss Tropical and Public Health Institute, 4002 Basel, Switzerland
[9] University of Basel, 4003 Basel, Switzerland
[10] INSERM, U945, Paris, France
[11] Université Pierre et Marie Curie-Paris (UPMC), UMR S, 945 Paris, France
[12] Assistance Publique-Hôpitaux de Paris, Groupe hospitatier Pitié-Salpêtrière, Service Parasitologie-Mycologie, Paris, France
[13] Entomology Department, AFRIMS, Bangkok 10400, Thailand
[14] Novartis Institutes for Tropical Disease, Singapore - Source
Science (Washington, D.C.). 2011, Vol 334, Num 6061, pp 1372-1377, 6 p ; ref : 30 ref
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antipaludique Antiparasitaire Mécanisme action Médicament Paludisme Parasitologie Pharmacothérapie Plasmodium Recherche et développement Structure chimique Apicomplexa Infection Parasitose Protozoa Protozoose Traitement
- Keyword (en)
- Biological activity Antimalarial Parasiticide Mechanism of action Drug Malaria Parasitology Pharmacotherapy Plasmodium Research and development Chemical structure Apicomplexa Infection Parasitosis Protozoa Protozoal disease Treatment
- Keyword (es)
- Actividad biológica Antipalúdico Antiparasitario Mecanismo acción Medicamento Paludismo Parasitología Farmacoterapia Plasmodium Investigación desarrollo Estructura química Apicomplexa Infección Parasitosis Protozoa Protozoosis Tratamiento
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents
- Discipline
- General pharmacology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25376374
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1211936 
https://dx.doi.org/10.1126/science.1211936
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