Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice
- Author
- QUAN, W1 ; HUR, K. Y1 ; KIM, K.-W1 ; KIM, J4 ; KOMATSU, M5 ; LEE, M.-S1 6 ; LIM, Y1 ; OH, S. H1 ; LEE, J.-C1 ; KIM, K. H1 ; KIM, G. H2 ; KIM, S.-W2 ; KIM, H. L3 ; LEE, M.-K1
[1] Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Kangnam-ku, Seoul 135-710, Korea, Republic of
[2] Department of Pharmacology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of
[3] Cell Death Disease Research Center, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of
[4] Department of Anatomy, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of
[5] Laboratory of Frontier Science, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
[6] Samsung Advanced Institute for Health Sciences and Technology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of - Source
Diabetologia (Berlin). 2012, Vol 55, Num 2, pp 392-403, 12 p ; ref : 36 ref
- ISSN
- 0012-186X
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Autophagy · Diabetes mellitus · Endoplasmic reticulum stress · Pancreatic beta cell · Unfolded protein response
- Keyword (fr)
- Animal Cellule β Diabète Déficit Etat nutritionnel Obésité Protéine Réticulum endoplasmique Souris Stress Endocrinopathie Ilot Langerhans Mammalia Pancréas endocrine Rodentia Trouble de la nutrition Vertebrata
- Keyword (en)
- Animal β Cell Diabetes mellitus Deficiency Nutritional status Obesity Protein Endoplasmic reticulum Mouse Stress Endocrinopathy Langerhans islet Mammalia Endocrine pancreas Rodentia Nutrition disorder Vertebrata
- Keyword (es)
- Animal Célula β Diabetes Déficiencia Estado nutricional Obesidad Proteína Retículo endoplásmico Ratón Estrés Endocrinopatía Isla Langerhans Mammalia Páncreas endocrino Rodentia Trastorno nutricíon Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity
- Discipline
- Endocrinopathies Metabolic diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25571506
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00125-011-2350-y 
https://dx.doi.org/10.1007/s00125-011-2350-y
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