Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
- Author
- NIKOLAEV, Sergey I1 ; RIMOLDI, Donata2 ; MICHIELIN, Olivier2 3 7 ; MUEHLETHALER, Katja2 ; SPEISER, Daniel2 ; BECKMANN, Jacques S4 8 ; XENARIOS, Ioannis3 ; HALAZONETIS, Thanos D9 ; VICTOR JONGENEEL, C10 11 2 3 ; STEVENSON, Brian J2 3 ; ANTONARAKIS, Stylianos E1 12 ; ISELI, Christian2 3 ; VALSESIA, Armand2 4 ; ROBYR, Daniel1 ; GEHRIG, Corinne1 ; HARSHMAN, Keith5 ; GUIPPONI, Michel1 ; BUKACH, Olesya6 ; ZOETE, Vincent3
[1] Department of Genetic Medicine and Development, University of Geneva, Geneva, Switzerland
[2] Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland
[3] Swiss Institute of Bioinformatics, Lausanne, Switzerland
[4] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland
[5] Lausanne Genomic Technologies Facility, Center for Integrative Genomics, Lausanne, Switzerland
[6] Department of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland
[7] Multidisciplinary Oncology Center, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland
[8] Service of Medical Genetics, CHUV, Lausanne, Switzerland
[9] Department of Molecular Biology, University of Geneva, Geneva, Switzerland
[10] National Center for Supercomputing Applications, University of Illinois, Urbana, Illinois, United States
[11] Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States
[12] Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland - Source
Nature genetics. 2012, Vol 44, Num 2, pp 133-139, 7 p ; ref : 43 ref
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Identification Mutation Mélanome malin Récidivant Séquençage Cancer Tumeur maligne
- Keyword (en)
- Identification Mutation Malignant melanoma Recurrent Sequencing Cancer Malignant tumor
- Keyword (es)
- Identificación Mutación Melanoma maligno Recidivante Sequencing Cáncer Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B08 Dermatology / 002B08A Tumors of the skin and soft tissue. Premalignant lesions
- Discipline
- Dermatology Eukaryotes genetics. Biological and molecular evolution
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25662246
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng.1026 
https://dx.doi.org/10.1038/ng.1026
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