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A phase I dose-escalation and pharmacokinetic study of enzastaurin and erlotinib in patients with advanced solid tumors

Author
PADDA, Sukhmani K1 2 ; KRUPITSKAYA, Yelena1 2 ; CHHATWANI, Laveena1 2 ; FISHER, George A1 2 ; COLEVAS, Alexander D1 2 ; SAN PEDRO-SALCEDO, Melanie1 2 ; DECKER, Rodney3 ; LATZ, Jane E3 ; WAKELEE, Heather A2
[1] Department of Medicine, Division of Oncology, Stanford University, 875 Blake Wilbur Drive, Stanford, CA 94305-5826, United States
[2] Stanford Cancer Institute, Stanford, CA, United States
[3] Eli Lilly and Company, Indianapolis, IN, United States
Source

Cancer chemotherapy and pharmacology. 2012, Vol 69, Num 4, pp 1013-1020, 8 p ; ref : 23 ref

CODEN
CCPHDZ
ISSN
0344-5704
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
Springer, Heidelberg
Publication country
Germany
Document type
Article
Language
English
Author keyword
Clinical trial Enzastaurin Erlotinib Pharmacokinetics
Keyword (fr)
Anticancéreux Chimiothérapie Dose croissante Enzastaurine Erlotinib Essai clinique Homme Malade Médicament Pharmacocinétique Stade avancé Tumeur solide Anti-EGFR Escalade de dose Inhibiteur de la tyrosine kinase de l'EGFR Cancer Dérivé de la quinazoline Enzyme Inhibiteur de la tyrosine kinase Inhibiteur enzyme Protein-tyrosine kinase Traitement Transferases Tumeur maligne
Keyword (en)
Antineoplastic agent Chemotherapy Increasing dose Enzastaurin Erlotinib Clinical trial Human Patient Drug Pharmacokinetics Advanced stage Solid tumor Dose escalation EGFR tyrosine kinase inhibitor Cancer Quinazoline derivatives Enzyme Tyrosine kinase inhibitor Enzyme inhibitor Protein-tyrosine kinase Treatment Transferases Malignant tumor
Keyword (es)
Anticanceroso Quimioterapia Dosis creciente Enzastaurina Erlotinib Ensayo clínico Hombre Enfermo Medicamento Farmacocinética Estadio avanzado Tumor sólido Cáncer Enzima Inhibidor tyrosine kinase Inhibidor enzima Protein-tyrosine kinase Tratamiento Transferases Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)

Discipline
Pharmacological treatments Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
25665494

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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