Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
- Author
- JIAN YANG1 2 ; FERREIRA, Teresa3 ; FRAYLING, Timothy M5 ; MCCARTHY, Mark I3 7 ; HIRSCHHORN, Joel N10 11 12 8 9 ; EGODDARD, Michael13 14 ; VISSCHER, Peter M1 15 2 ; MORRIS, Andrew P3 ; MEDLAND, Sarah E1 ; MADDEN, Pamela A. F4 ; HEATH, Andrew C4 ; MARTIN, Nicholas G1 ; MONTGOMERY, Grant W1 ; WEEDON, Michael N5 ; LOOS, Ruth J6
[1] Queensland Institute of Medical Research, Brisbane, Queensland, Australia
[2] University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia
[3] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
[4] Department of Psychiatry, Washington University, Saint Louis, Missouri, United States
[5] Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom
[6] Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom
[7] Oxford Centre for Diabetes, Endocrinology and Metabolism, Headington, Oxford, United Kingdom
[8] Program in Genomics, Children's Hospital, Boston, Massachusetts, United States
[9] Division of Genetics, Children's Hospital, Boston, Massachusetts, United States
[10] Division of Endocrinology, Children's Hospital, Boston, Massachusetts, United States
[11] Broad Institute, Cambridge, Massachusetts, United States
[12] Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States
[13] Department of Food and Agricultural Systems, The University of Melbourne, Parkville, Victoria, Australia
[14] Biosciences Research Division, Department of Primary Industries, Bundoora, Victoria, Australia
[15] The Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia - Source
Nature genetics. 2012, Vol 44, Num 4, pp 369-375, 7 p ; ref : 27 ref
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Articulation Identification Polygénique Polymorphisme mononucléotide Statistique Variant Système ostéoarticulaire
- Keyword (en)
- Joint Identification Polygenic Single nucleotide polymorphism Statistics Variant Osteoarticular system
- Keyword (es)
- Articulación Identificación Poligénico Polimorfismo mononucleótido Estadística Variante Sistema osteoarticular
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution
- Discipline
- Eukaryotes genetics. Biological and molecular evolution
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25767233
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng.2213 
https://dx.doi.org/10.1038/ng.2213
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