Investigation of the Mechanism of Clearance of AMG 386, a Selective Angiopoietin-I/2 Neutralizing Peptibody, in Splenectomized, Nephrectomized, and FcRn Knockout Rodent Models
- Author
- WU, Benjamin1 ; JOHNSON, Jessica1 ; SOTO, Marcus1 ; PONCE, Manuel1 ; CALAMBA, Dominador1 ; SUN, Yu-Nien1
[1] Department of Pharmacokinetics & Drug Metabolism, Amgen Inc. One Amgen Center Drive, Mailstop 28-3-B, Thousand Oaks, California, United States - Source
Pharmaceutical research. 2012, Vol 29, Num 4, pp 1057-1065, 9 p ; ref : 40 ref
- CODEN
- PHREEB
- ISSN
- 0724-8741
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- AMG 386 clearance mechanism neonatal Fc nephrectomy peptibody receptor
- Keyword (fr)
- Animal Clairance Mécanisme action Néonatal Rodentia Récepteur biologique Souris knockout Technologie pharmaceutique Mammalia Pharmacocinétique Vertebrata
- Keyword (en)
- Animal Clearance Mechanism of action Neonatal Rodentia Biological receptor Knockout mouse Pharmaceutical technology Mammalia Pharmacokinetics Vertebrata
- Keyword (es)
- Animal Depuración Mecanismo acción Neonatal Rodentia Receptor biológico Ratón knockout Tecnología farmacéutica Mammalia Farmacocinética Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 25795671
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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