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Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress

Author
TANG, C1 ; KOULAJIAN, K1 ; VOLCHUK, A2 ; GIACCA, A1 ; SCHUIKI, I2 ; ZHANG, L2 ; DESAI, T1 ; IVOVIC, A1 ; WANG, P3 ; ROBSON-DOUCETTE, C1 ; WHEELER, M. B1 ; MINASSIAN, B3
[1] Department of Physiology, University of Toronto, Medical Science Building, Room 3336, 1 King's College Circle, Toronto, ON M5S 1A8, Canada
[2] Division of Cellular and Molecular Biology, Toronto General Research Institute, University Health Network, Toronto, ON, Canada
[3] Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada
Source

Diabetologia (Berlin). 2012, Vol 55, Num 5, pp 1366-1379, 14 p ; ref : 44 ref

ISSN
0012-186X
Scientific domain
Endocrinology; Nutrition, obesity, metabolic disorders
Publisher
Springer, Heidelberg
Publication country
Germany
Document type
Article
Language
English
Author keyword
Beta cell dysfunction Endoplasmic reticulum stress Glucotoxicity In vivo Oxidative stress
Keyword (fr)
Animal Cellule β Diabète Glucose In vivo Rat Réticulum endoplasmique Stress oxydatif Trouble fonctionnel Endocrinopathie Ilot Langerhans Mammalia Pancréas endocrine Rodentia Vertebrata
Keyword (en)
Animal β Cell Diabetes mellitus Glucose In vivo Rat Endoplasmic reticulum Oxidative stress Dysfunction Endocrinopathy Langerhans islet Mammalia Endocrine pancreas Rodentia Vertebrata
Keyword (es)
Animal Célula β Diabetes Glucosa In vivo Rata Retículo endoplásmico Estrés oxidativo Trastorno funcional Endocrinopatía Isla Langerhans Mammalia Páncreas endocrino Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance

Discipline
Endocrinopathies
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
25850838

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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