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The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Author
HAWLEY, Simon A1 ; FULLERTON, Morgan D2 ; KEMP, Bruce E4 ; SAKAMOTO, Kei3 ; STEINBERG, Gregory R2 4 ; HARDIE, D. Grahame1 ; ROSS, Fiona A1 ; SCHERTZER, Jonathan D2 ; CHEVTZOFF, Cyrille1 ; WALKER, Katherine J1 ; PEGGIE, Mark W3 ; ZIBROVA, Darya3 ; GREEN, Kevin A1 ; MUSTARD, Kirsty J1
[1] Division of Cell Signalling and Immunology, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom
[2] Divisions of Endocrinology and Metabolism, Department of Medicine, and Department of Biochemistry and Biomedical Sciences, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
[3] Medical Research Council Protein Phosphorylation Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom
[4] St. Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, Vic 3065, Australia
Source

Science (Washington, D.C.). 2012, Vol 336, Num 6083, pp 918-922, 5 p ; ref : 30 ref

CODEN
SCIEAS
ISSN
0036-8075
Scientific domain
Multidisciplinary
Publisher
American Association for the Advancement of Science, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Animal In vivo Médicament Souris knockout cAMP-dependent protein kinase Activateur de l'AMPK Salicylate
Keyword (en)
Animal In vivo Drug Knockout mouse cAMP-dependent protein kinase AMPK activator
Keyword (es)
Animal In vivo Medicamento Ratón knockout cAMP-dependent protein kinase
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
25901975

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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