A Single-Nucleotide Polymorphism in the Methylene Tetrahydrofolate Reductase (MTHFR) Gene Is Associated With Risk of Radiation Pneumonitis in Lung Cancer Patients Treated With Thoracic Radiation Therapy
- Author
- MAK, Raymond H1 ; ALEXANDER, Brian M2 ; WILLERS, Henning6 ; CHOI, Noah C6 ; CHRISTIANI, David C3 ; ASOMANING, Kofi3 ; HEIST, Rebecca S3 4 ; LIU, Chen-Yu3 5 ; LI SU3 ; RIHONG ZHAI3 ; ANCUKIEWICZ, Marek6 ; NAPOLITANO, Brian6 ; NIEMIERKO, Andrzej6
[1] Harvard Radiation Oncology Program, Boston, Massachusetts, United States
[2] Department of Radiation Oncology, Brigham and Women's Hospital, Boston, Massachusetts, United States
[3] Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States
[4] Division of Hematology/Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States
[5] Institute of Environmental Health, National Taiwan University, Taipei, Taiwan, Province of China
[6] Department of Radiation Oncology, Massachusetts General Hospital Boston, Massachusetts, United States - Source
Cancer. 2012, Vol 118, Num 14, pp 3654-3665, 12 p ; ref : 21 ref
- CODEN
- CANCAR
- ISSN
- 0008-543X
- Scientific domain
- Medical oncology
- Publisher
- Wiley-Blackwell, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- MTHFR lung cancer oxidative stress radiation pneumonitis single-nucleotide polymorphism
- Keyword (fr)
- Cancer du poumon Cancérologie Facteur risque Gène Génotype Génétique Homme Methylenetetrahydrofolate reductase (NADPH) Pneumonie Polymorphisme mononucléotide Radiothérapie Stress oxydatif Traitement Variabilité génétique Cancer Enzyme Oxidoreductases Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons Tumeur maligne
- Keyword (en)
- Lung cancer Cancerology Risk factor Gene Genotype Genetics Human Methylenetetrahydrofolate reductase (NADPH) Pneumonia Single nucleotide polymorphism Radiotherapy Oxidative stress Treatment Genetic variability Cancer Enzyme Oxidoreductases Respiratory disease Bronchus disease Lung disease Malignant tumor
- Keyword (es)
- Cáncer del pulmón Cancerología Factor riesgo Gen Genotipo Genética Hombre Methylenetetrahydrofolate reductase (NADPH) Neumonía Polimorfismo mononucleótido Radioterapia Estrés oxidativo Tratamiento Variabilidad genética Cáncer Enzima Oxidoreductases Aparato respiratorio patología Bronquio patología Pulmón patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pulmonology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26098561
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/cncr.26667 
https://dx.doi.org/10.1002/cncr.26667
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