Synthesis and characterization of 2'-C-Me branched C-nucleosides as HCV polymerase inhibitors
- Author
- CHO, Aesop1 ; LIJUN ZHANG1 ; FENG, Joy Y1 ; RAY, Adrian S1 ; KIM, Choung U1 ; JIE XU1 ; BABUSIS, Darius1 ; BUTLER, Thomas1 ; LEE, Rick1 ; SAUNDERS, Oliver L1 ; TING WANG1 ; PARRISH, Jay1 ; PERRY, Jason1
[1] Gilead Sciences, 333 Lakeside Drive, Foster City, CA 94044, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 12, pp 4127-4132, 6 p ; ref : 25 ref
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Antiviral C-Nucleoside HCV Polymerase inhibitor
- Keyword (fr)
- Antiviral C-Nucléoside Composé ramifié DNA-directed DNA polymerase Inhibiteur de l'ADN polymérase Inhibiteur enzyme Nucléoside RNA-directed RNA polymerase Synthèse chimique Virus hépatite C NS5B polymerase Protéine NS5B Enzyme Flaviviridae Hepacivirus Nucleotidyltransferases Transferases Virus
- Keyword (en)
- Antiviral C-Nucleoside Branched compound DNA-directed DNA polymerase DNA polymerase inhibitor Enzyme inhibitor Nucleoside RNA-directed RNA polymerase Chemical synthesis Hepatitis C virus Enzyme Flaviviridae Hepacivirus Nucleotidyltransferases Transferases Virus
- Keyword (es)
- Antiviral C-Nucleósido Compuesto ramificado DNA-directed DNA polymerase Inhibidor DNA polymerase Inhibidor enzima Nucleósido RNA-directed RNA polymerase Síntesis química Hepatitis C virus Enzima Flaviviridae Hepacivirus Nucleotidyltransferases Transferases Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26103353
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2012.04.065 
https://dx.doi.org/10.1016/j.bmcl.2012.04.065
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