A new facile synthetic route to [11C]GSK189254, a selective PET radioligand for imaging of CNS histamine H3 receptor
- Author
- MIN WANG1 ; MINGZHANG GAO1 ; STEELE, Brandon L1 ; GLICK-WILSON, Barbara E1 ; BROWN-PROCTOR, Clive1 ; SHEKHAR, Anantha2 ; HUTCHINS, Gary D1 ; ZHENG, Qi-Huang1
[1] Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 1345 West 16th Street, Room 202, Indianapolis, IN 46202, United States
[2] Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 14, pp 4713-4718, 6 p ; ref : 41 ref
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Automation Brain imaging Histamine H3 receptor Positron emission tomography (PET) Radiosynthesis [11C]GSK189254
- Keyword (fr)
- Agent scintigraphique Automatisation Carbone Isotope Formation image Imagerie médicale Ligand Marquage radioisotopique Récepteur histaminergique H3 Synthèse chimique Système nerveux central Sélectivité Tomographie par émission de positons Carbone 11 Radioligand Radiosynthèse
- Keyword (en)
- Scintigraphic agent Automation Carbon Isotopes Imaging Medical imagery Ligand Radiolabelling H3 histamine receptor Chemical synthesis Central nervous system Selectivity Positron emission tomography
- Keyword (es)
- Agente centelleográfico Automatización Carbono Isótopo Formación imagen Imaginería médica Ligando Marcación radioisotópica Receptor histaminérgico H3 Síntesis química Sistema nervioso central Selectividad Tomografía emisión positrones
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02P Genital system. Reproduction
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26151481
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2012.05.076 
https://dx.doi.org/10.1016/j.bmcl.2012.05.076
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