Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

Auteur

ROZENBLATT-ROSEN, Orit^{1 2 3} ; DEO, Rahul C^{1 4 5} ; PEVZNER, Samuel J^{10 13 9} ; ABDERAZZAQ, Fieda^{1 6} ; BYRDSON, Danielle^{1 10 9} ; CARVUNIS, Anne-Ruxandra^{10 9} ; CHEN, Alyce A^{1 12} ; JINGWEI CHENG^{2 3} ; CORRELL, Mick⁶ ; DUARTE, Melissa^{1 11 9} ; CHANGYU FAN^{1 10 9} ; FELTKAMP, Mariet C¹⁴ ; PADI, Megha^{1 6 7} ; FICARROL, Scott B^{1 4 8} ; FRANCHI, Rachel^{1 15 9} ; GARG, Brijesh K^{1 4 8} ; GULBAHCE, Natali^{1 16 17 9} ; TONG HAO^{10 9} ; HOLTHAUS, Amy M¹¹ ; JAMES, Robert^{10 9} ; KORKHIN, Anna^{2 3} ; LITOVCHICK, Larisa^{2 3} ; MAR, Jessica C^{6 7} ; ADELMANT, Guillaume^{1 4 8} ; PAK, Theodore R¹⁸ ; RABELLO, Sabrina^{16 3 9} ; RUBIO, Renee⁶ ; YUN SHEN^{10 9} ; SINGH, Saurav^{4 8} ; SPANGLE, Jennifer M¹² ; TASAN, Murat^{18 4} ; WANAMAKER, Shelly^{10 15 9} ; WEBBER, James T^{4 8} ; ROECKLEIN-CANFIELD, Jennifer^{15 9} ; CALDERWOOD, Michael A^{1 10 11 9} ; JOHANNSEN, Eric¹¹ ; BARABASI, Albert-László^{16 3 9} ; BEROUKHIM, Rameen^{19 20 3} ; KIEFF, Elliott¹¹ ; CUSICK, Michael E^{10 9} ; HILL, David E^{10 9} ; MÜNGER, Karl¹² ; MARTO, Jarrod A^{4 8} ; QUACKENBUSH, John^{6 7} ; ROTH, Frederick P^{18 4} ; ROLLAND, Thomas^{1 10 9} ; DECAPRIO, James A^{2 3} ; VIDAL, Marc¹⁰ ; GRACE, Miranda^{1 12} ; DRICOT, Amélie^{1 10 9} ; ASKENAZI, Manor^{1 4 8} ; TAVARES, Maria^{1 2 3 8}
[1] Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States
[2] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States
[3] Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States
[4] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States
[5] Cardiovascular Research Institute, Department of Medicine and Institute for Human Genetics, University of California, San Francisco, California 94143, United States
[6] Center for CancerComputational Biology (CCCB), Department of Biostatistics and Computational Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States
[7] Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, United States
[8] Blais Proteomics Center and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States
[9] Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States
[10] DepartmentofGenetics, Harvard Medical School, Boston, Massachusetts 02115, United States
[11] Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Departments of Medicine and of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts 02115, United States
[12] Division of Infectious Diseases, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, United States
[13] Biomedical Engineering Department, Boston University and Boston University School of Medicine, Boston, Massachusetts 02118, United States
[14] Department of Medical Microbiology, Leiden University Medical Center, 2300 RC Leiden, Netherlands
[15] Department of Chemistry, Simmons College, Boston, Massachusetts 02115, United States
[16] Center for Complex Networks Research (CCNR) and Department of Physics, Northeastern University, Boston, Massachusetts 02115, United States
[17] Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94158, United States
[18] Donnelly Centre and Departments of Molecular Genetics and Computer Science, University of Toronto and Lunenfeld Research Institute, Mt Sinai Hospital, Toronto, Ontario M5G 1X5, Canada
[19] Department of Medical Oncology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States
[20] The Broad Institute, Cambridge, Massachusetts 02142, United States

Source

Nature (London). 2012, Vol 487, Num 7408, pp 491-495, 5 p ; ref : 29 ref

CODEN

NATUAS

ISSN

0028-0836

Domaine scientifique

Multidisciplinary

Editeur

Nature Publishing Group, London

Pays de publication

United Kingdom

Type de document

Article

Langue

English

Mot clé (fr)

Cancer Cancérologie Génome Homme Protéine Relation hôte tumeur Tumeur maligne Virus Génétique

Mot clé (en)

Cancer Cancerology Genome Human Protein Host tumor relation Malignant tumor Virus Genetics

Mot clé (es)

Cáncer Cancerología Genoma Hombre Proteína Relación huesped tumor Tumor maligno Virus Genética

Classification

Pascal

002 Sciences biologiques et medicales / 002B Sciences medicales / 002B04 Tumeurs / 002B04F Relations hôte-tumeurs. Immunologie. Marqueurs biologiques

Discipline

Tumours

Provenance

Inist-CNRS

Base de données

PASCAL

Identifiant INIST

26163560

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS