A Functional Tph2 C1473G Polymorphism Causes an Anxiety Phenotype via Compensatory Changes in the Serotonergic System
- Author
- BERGER, Stefan M1 ; WEBER, Tillmann1 2 3 ; PERREAU-LENZ, Stephanie4 ; VOGT, Miriam A5 ; GARTSIDE, Sarah E6 ; MASER-GLUTH, Christiane7 ; LANFUMEY, Laurence8 ; GASS, Peter5 ; SPANAGEL, Rainer4 ; BARTSCH, Dusan1
[1] Department of Molecular Biology, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany
[2] Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannhelm/Heldelberg University, Mannheim, Germany
[3] Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/ Heidelberg University, Mannheim, Germany
[4] Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannhelm/ Heidelberg University, Mannheim, Germany
[5] Department of Psychiatry and Psychotherapy, Research Group Animal Models in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heldelberg University, Mannheim, Germany
[6] Institute of Neuroscience, The Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom
[7] Steroid Laboratory, Department of Pharmacology, University of Heidelberg, Heidelberg, Germany
[8] INSERM UMRS894, CPN, Unlverslté Pierre and Marie Curie, Paris, France - Source
Neuropsychopharmacology (New York, NY). 2012, Vol 37, Num 9, pp 1986-1998, 13 p ; ref : 2 p
- CODEN
- NEROEW
- ISSN
- 0893-133X
- Scientific domain
- Cognition; Neurology; Pharmacology drugs; Psychology, psychopathology, psychiatry
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- 5-HTIA receptor SSRI TPH2 anxiety depression serotonin
- Keyword (fr)
- Angoisse anxiété Compensation Etat dépressif Inhibiteur sélectif recapture sérotonine Phénotype Polymorphisme Récepteur biologique Sérotonine Neurotransmetteur Trouble de l'humeur
- Keyword (en)
- Anxiety Compensation Depression Selective serotonin reuptake inhibitor Phenotype Polymorphism Biological receptor Serotonin Neurotransmitter Mood disorder
- Keyword (es)
- Angustia ansiedad Compensación Estado depresivo Inhibidor selectivo recaptura serotonin Fenotipo Polimorfismo Receptor biológico Serotonina Neurotransmisor Trastorno humor
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C07 Mood disorders / 002B18C07A Depression
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D03 Adult and adolescent clinical studies / 770-D03G Mood disorders / 770-D03G01 Depression
- Discipline
- Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 26175568
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/npp.2012.46 
https://dx.doi.org/10.1038/npp.2012.46
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