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Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche

Author
SCENEAY, Jaclyn1 4 ; CHOW, Melvyn T2 4 ; MÖLLER, Andreas1 4 5 6 ; CHEW, Anna1 4 ; HALSE, Heloise M2 ; WONG, Christina S. F1 ; ANDREWS, Daniel M2 ; SLOAN, Erica K7 ; PARKER, Belinda S3 4 5 ; BOWTELL, David D1 4 5 6 ; SMYTH, Mark J2 4 5 6
[1] Cancer Genomics and Genetics Laboratory, United States
[2] Cancer Immunology Program, and, United States
[3] Metastasis Research Group, Peter MacCallum Cancer Centre, St. Andrews Place, East Melbourne, United States
[4] Department of Pathology, The University of Melbourne, United States
[5] Sir Peter MacCallum Department of Oncology, The University of Melbourne, United States
[6] Department of Biochemistry, The University of Melbourne, United States
[7] Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
Source

Cancer research (Chicago, Ill.). 2012, Vol 72, Num 16, pp 3906-3911, 6 p ; ref : 20 ref

CODEN
CNREA8
ISSN
0008-5472
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
American Association for Cancer Research, Philadelphia, PA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Cellule NK Cellule suppressive Cytotoxicité Hypoxie Oxygène Primaire Tumeur maligne Cancer
Keyword (en)
Natural killer cell Suppressive cell Cytotoxicity Hypoxia Oxygen Primary Malignant tumor Cancer
Keyword (es)
Célula NK Célula supresora Citotoxicidad Hipoxia Oxígeno Primario Tumor maligno Cáncer
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
Pharmacological treatments Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
26285856

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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