Transforming growth factor-beta1 induces microvascular abnormalities through a down- modulation of neural cell adhesion molecule in human hepatocellular carcinoma
- Author
- BALZARINI, Piera1 ; BENETTI, Anna1 ; PORTOLANI, Nazario5 ; GIULINI, Stefano M5 ; FERRARI, Maura6 ; CIUSANI, Emilio7 ; NAVONE, Stefania E2 ; CANAZZA, Alessandra2 ; PARATI, Eugenio A2 ; ALESSANDRI, Giulio2 ; INVERNICI, Gloria2 ; CRISTINI, Silvia2 ; ZICARI, Sonia3 ; CARUSO, Arnaldo3 ; GATTA, Luisa B1 ; BERENZI, Angiola1 ; IMBERTI, Luisa4 ; ZANOTTI, Cinzia4
[1] Second Department of Pathology, University of Brescia and Spedali Civili, Brescia, Italy
[2] Laboratory of Cellular Neurobiology, Department of Cerebrovascular Diseases, IRCCS Foundation Neurological Institute 'Carlo Besta', Milan, Italy
[3] Department of Microbiology, University of Brescia and Spedali Civili, Brescia, Italy
[4] Biotechnology Laboratory, Diagnostics Department, Spedali Civili, Brescia, Italy
[5] Department of Medical and Surgical Science, University of Brescia and Spedali Civili, Brescia, Italy
[6] Experimental Zooprofilattico Institute of Lombardia and Emilia Romagna, Brescia, Italy
[7] Department of Diagnostic and Applied Technology, IRCCS Foundation Neurological Institute 'Carlo Besta', Milan, Italy - Source
Laboratory investigation. 2012, Vol 92, Num 9, pp 1297-1309, 13 p ; ref : 56 ref
- CODEN
- LAINAW
- ISSN
- 0023-6837
- Scientific domain
- Biochemistry, molecular biology, biophysics; Medical laboratory techniques; General medicine general surgery
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- HCC NCAM TGF-β1 adhesion molecules angiogenesis stromal cells vascular abnormalities
- Keyword (fr)
- Angiogenèse Anomalie Biologie clinique Biotechnologie Cancer du foie Carcinome hépatocellulaire Cellule stromale Facteur croissance transformant β1 Facteur croissance transformant Homme Microcirculation Modulation Néovascularisation Protéine CAM Protéine NCAM Vaisseau sanguin Appareil circulatoire Cancer Pathologie de l'appareil digestif Pathologie du foie Tumeur maligne
- Keyword (en)
- Angiogenesis Anomaly Clinical biology Biotechnology Liver cancer Hepatocellular carcinoma Stromal cell Transforming growth factor β1 Transforming growth factor Human Microcirculation Modulation Neovascularization Cell adhesion molecule Neural cell adhesion molecule Blood vessel Circulatory system Cancer Digestive diseases Hepatic disease Malignant tumor
- Keyword (es)
- Angiogénesis Anomalía Biología clínica Biotecnología Cáncer del hígado Carcinoma hepatocelular Célula estromal Factor crecimiento transformante β1 Factor crecimiento transformante Hombre Microcirculación Modulación Neovascularización Proteína CAM Proteína NCAM Vaso sanguíneo Aparato circulatorio Cáncer Aparato digestivo patología Hígado patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C01 Tumors
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B24 Investigative techniques, diagnostic techniques (general aspects)
- Discipline
- Biotechnology Gastroenterology. Liver. Pancreas. Abdomen Scanning and diagnostic techniques
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26429985
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/labinvest.2012.94 
https://dx.doi.org/10.1038/labinvest.2012.94
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