POMA analyses as new efficient bioinformatics' platform to predict and optimise bioactivity of synthesized 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues
- Author
- MOHAMED JAWED AHSAN1 2 ; GOVINDASAMY, Jeyabalan1 ; KHALILULLAH, Habibullah1 ; MOHAN, Govind2 ; STABLES, James P3 ; PANNECOUQUE, Christophe4 ; DE CLERCQ, Eric4
[1] New Drug Discovery Research, Department of Medicinal Chemistry, Alwar Pharmacy College, Alwar, Rajasthan 301 030, India
[2] Department of Pharmaceutical Chemistry, Nims Institute of Pharmary, Nims University, Jaipur, Rajasthan 303 121, India
[3] Preclinical Pharmacology Section, Epilepsy Branch, National Institute of Health, Bethesda, MD 20892-9020, United States
[4] Rega Institute for Medical Research, Katholieke Universiteit Leuven, 3000 Leuven, Belgium - Source
Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 23, pp 7029-7035, 7 p ; ref : 30 ref
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Anti-HIV Antibacterial Anticonvulsant Antifungal Petra/Osiris/Molinspiration/ALOGPS 2.1 Pyrazolines Tautomerism program
- Keyword (fr)
- Activité biologique Antibactérien Anticonvulsivant Antifongique Antirétroviral Antiviral Bioinformatique Carboxamide Dérivé du pyrazole Prédiction Synthèse chimique Tautomérie Thioamide Virus immunodéficience humaine Anti hiv Indéno[1,2-c]pyrazole dérivé Indénopyrazole Pyrazoline dérivé Lentivirus Retroviridae Virus
- Keyword (en)
- Biological activity Antibacterial agent Anticonvulsant Antifungal agent Antiretroviral agent Antiviral Bioinformatics Carboxamide Pyrazole derivatives Prediction Chemical synthesis Tautomerism Thioamide Human immunodeficiency virus Lentivirus Retroviridae Virus
- Keyword (es)
- Actividad biológica Antibacteriano Anticonvulsivante Antifúngico Antiretroviral Antiviral Bioinformática Carboxamida Pirazol derivado Predicción Síntesis química Tautomeria Tioamida Human immunodeficiency virus Lentivirus Retroviridae Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B06 Anticonvulsants. Antiepileptics. Antiparkinson agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S04 Antifungal agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26624142
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2012.09.108 
https://dx.doi.org/10.1016/j.bmcl.2012.09.108
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