Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress―Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis
- Author
- CUNHA, Daniel A1 ; IGOILLO-ESTEVE, Mariana1 ; MARSELLI, Lorella4 ; MARCHETTI, Piero4 ; HARDING, Heather P5 ; RON, David5 ; EIZIRIK, Décio L1 ; CNOP, Miriam1 6 ; GURZOV, Esteban N1 ; GERMANO, Carla M1 ; NAAMANE, Najib1 ; MARHFOUR, Ihsane1 ; FUKAYA, Makiko1 ; VANDERWINDEN, Jean-Marie2 ; GYSEMANS, Conny3 ; MATHIEU, Chantal3
[1] Laboratory of Experimental Medicine, Université Libre de Bruxelles, Brussels, Belgium
[2] Laboratory of Neurophysiology, Université Libre de Bruxelles, Brussels, Belgium
[3] Laboratory of Experimental Medicine Endocrinology (LEGENDO), Faculty of Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
[4] Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
[5] University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Cambridge, United Kingdom
[6] Division of Endocrinology, Erasmus Hospital, Université Libre de Bruxelles, Brussels, Belgium - Source
Diabetes (New York, NY). 2012, Vol 61, Num 11, pp 2763-2775, 13 p ; ref : 51 ref
- CODEN
- DIAEAZ
- ISSN
- 0012-1797
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- American Diabetes Association, Alexandria, VA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Apoptose Cellule β Diabète Homme Mitochondrie Protéine p53 Rodentia Réticulum endoplasmique Stress Endocrinopathie Ilot Langerhans Mammalia Mort cellulaire Pancréas endocrine Vertebrata
- Keyword (en)
- Apoptosis β Cell Diabetes mellitus Human Mitochondria p53 Protein Rodentia Endoplasmic reticulum Stress Endocrinopathy Langerhans islet Mammalia Cell death Endocrine pancreas Vertebrata
- Keyword (es)
- Apoptosis Célula β Diabetes Hombre Mitocondria Proteína p53 Rodentia Retículo endoplásmico Estrés Endocrinopatía Isla Langerhans Mammalia Muerte celular Páncreas endocrino Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Discipline
- Endocrinopathies
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26691104
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2337/db12-0123 
https://dx.doi.org/10.2337/db12-0123
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