Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

Author

RICHTER, Julia¹ ; SCHLESNER, Matthias² ; LENZE, Dido⁸ ; SZCZEPANOWSKI, Monika⁹ ; PAULSEN, Maren¹⁰ ; LIPINSKI, Simone¹⁰ ; RUSSELL, Robert B¹¹ ; ADAM-KLAGES, Sabine¹² ; APIC, Gordana¹¹ ; CLAVIEZ, Alexander¹³ ; HASENCLEVER, Dirk⁴ ; HOVESTADT, Volker¹⁴ ; HOFFMANN, Steve³ ; HORNIG, Nadine¹ ; KORBEL, Jan O¹⁵ ; KUBE, Dieter¹⁶ ; LANGENBERGER, David³ ; LAWERENZ, Chris² ; LISFELD, Jasmin⁷ ; MEYER, Katharina¹⁷ ; PICELLI, Simone¹⁴ ; PISCHIMAROV, Jordan⁵ ; RADLWIMMER, Bernhard¹⁴ ; KREUZ, Markus⁴ ; RAUSCH, Tobias¹⁵ ; ROHDE, Marius⁷ ; SCHILHABEL, Markus¹⁰ ; SCHOLTYSIK, René¹⁸ ; SPANG, Rainer¹⁷ ; TRAUTMANN, Heiko¹⁹ ; ZENZ, Thorsten^{20 21 22} ; BORKHARDT, Arndt²³ ; DREXLER, Hans G²⁴ ; MÖLLER, Peter²⁵ ; LEICH, Ellen⁵ ; MACLEOD, Roderick A. F²⁴ ; POTT, Christiane¹⁹ ; SCHREIBER, Stefan; TRÜMPER, Lorenz¹⁶ ; LOEFFLER, Markus⁴ ; STADLER, Peter F; LICHTER, Peter¹⁴ ; EILS, Roland² ; KÜPPERS, Ralf¹⁸ ; HUMMEL, Michael⁸ ; BURKHARDT, Birgit^{6 7} ; KLAPPER, Wolfram⁹ ; ROSENSTIEL, Philip¹⁰ ; ROSENWALD, Andreas⁵ ; BRORS, Benedikt² ; SIEBERT, Reiner¹ ; ROSOLOWSKI, Maciej⁴ ; AMMERPOHL, Ole¹ ; WAGENER, Rabea¹ ; BERNHART, Stephan H³
[1] Institute of Human Genetics, Christian-Albrechts-University, Kiel, Germany
[2] Division of Theoretical Bioinformatics, Deutsches Krebsforschungszentrum Heidelberg (DKFZ), Heidelberg, Germany
[3] Transcriptome Bioinformatics, LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany
[4] Institute for Medical Informatics Statistics and Epidemiology, University of Leipzig, Leipzig, Germany
[5] Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany
[6] Pediatric Hematology and Oncology, University Hospital Muenster, Muenster, Germany
[7] Pediatric Hematology and Oncology, University Hospital Giessen, Giessen, Germany
[8] Institute of Pathology, Charité―University Medicine Berlin, Berlin, Germany
[9] Hematopathology Section, Christian-Albrechts-University, Kiel, Germany
[10] Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany
[11] Cell Networks, Bioquant, University of Heidelberg, Heidelberg, Germany
[12] Institute of Immunology, Christian-Albrechts-University, Kiel, Germany
[13] Department of Pediatrics, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
[14] Division of Molecular Genetics, DKFZ, Heidelberg, Germany
[15] Genome Biology Research Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
[16] Department of Hematology and Oncology, Georg-Augusts-University of Göttingen, Gottingen, Germany
[17] Institute of Functional Genomics, University of Regensburg, Regensburg, Germany
[18] Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, Duisburg-Essen, Medical School, Essen, Germany
[19] Department of Internal Medicine II, Hematology and Oncology, University Medical Centre, Campus Kiel, Kiel, Germany
[20] Department of Medicine V, University of Heidelberg, Heidelberg, Germany
[21] Department of Translational Oncology, National Center for Tumor Diseases (NCT) and DKFZ, Heidelberg, Germany
[22] Department of Medicine III, Ulm University, Ulm, Germany
[23] Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine-University, Düsseldorf, Germany
[24] Department of Human and Animal Cell Cultures, German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany
[25] Institute of Pathology, Medical Faculty of the Ulm University, Ulm, Germany
ICGC MMML-Seq Project

Source

Nature genetics. 2012, Vol 44, Num 12, pp 1316-1320, 5 p ; ref : 27 ref

CODEN

NGENEC

ISSN

1061-4036

Scientific domain

Genetics

Publisher

Nature Publishing Group, New York, NY

Publication country

United States

Document type

Article

Language

English

Keyword (fr)

Gène Génome Lymphome Burkitt Mutation Récidivant Séquençage Transcriptome Transcriptomique Cancer Hémopathie maligne Infection Lymphome non hodgkinien Syndrome lymphoprolifératif Virose

Keyword (en)

Gene Genome Burkitt lymphoma Mutation Recurrent Sequencing Transcriptome Transcriptomics Cancer Malignant hemopathy Infection Non Hodgkin lymphoma Lymphoproliferative syndrome Viral disease

Keyword (es)

Gen Genoma Linfoma Burkitt Mutación Recidivante Sequencing Transcriptoma Cáncer Hemopatía maligna Infección Linfoma no Hodgkin Linfoproliferativo síndrome Virosis

Classification

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C05 Transcription. Transcription factor. Splicing. Rna processing

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline

Blood diseases Eukaryotes genetics. Biological and molecular evolution Molecular and cell biology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

26701576

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS