High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

Author

EYRE, Steve^{1 2} ; BOWES, John^{1 2} ; AMOS, Christopher I⁹ ; PADYUKOV, Leonid¹⁰ ; TOES, Rene E. M⁷ ; HUIZINGA, Tom W. J⁷ ; WIJMENGA, Cisca⁸ ; TRYNKA, Gosia^{3 4 5 8} ; FRANKE, Lude⁸ ; WESTRA, Harm-Jan⁸ ; ALFREDSSON, Lars¹¹ ; XINLI HU^{12 3 4 5} ; DIOGO, Dorothée^{3 4 5} ; SANDOR, Cynthia^{3 4 5} ; DE BAKKER, Paul I. W^{13 14 3 4 5} ; DAVILA, Sonia¹⁵ ; CHIEA CHUEN KHOR¹⁵ ; KHAI KOON HENG¹⁵ ; ANDREWS, Robert¹⁶ ; EDKINS, Sarah¹⁶ ; HUNT, Sarah E¹⁶ ; LANGFORD, Cordelia¹⁶ ; SYMMONS, Deborah^{1 2} ; LEE, Annette⁶ ; CONCANNON, Pat¹⁷ ; ONENGUT-GUMUSCU, Suna¹⁷ ; RICH, Stephen S¹⁷ ; DELOUKAS, Panos¹⁶ ; GONZALEZ-GAY, Miguela¹⁸ ; RODRIGUEZ-RODRIGUEZ, Luis¹⁹ ; ARLSETIG, Lisbeth^{20 21} ; MARTIN, Javier²² ; RANTAPÄÄ-DAHLQVIST, Solbritt^{20 21} ; PLENGE, Robert M^{3 4 5} ; BARTON, Anne^{1 2} ; RAYCHAUDHURI, Soumya^{1 2 3 4 5} ; KLARESKOG, Lars¹⁰ ; GREGERSEN, Peter K⁶ ; WORTHINGTON, Jane^{1 2} ; MARTIN, Paul^{1 2} ; ZHERNAKOVA, Alexandra^{7 8} ; STAHL, Eli^{3 4 5} ; VIATTE, Sebastien^{1 2} ; MCALLISTER, Kate^{1 2}
[1] Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom
[2] National Institute for Health Research, Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals National Health Service Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, United Kingdom
[3] Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
[4] Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
[5] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States
[6] The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, New York, United States
[7] Department of Rheumatology, Leiden University Medical Centre, Leiden, Netherlands
[8] Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, Netherlands
[9] University of Texas MD Anderson Cancer Center, Houston, Texas, United States
[10] Rheumatology Unit, Department of Medicine, Karolinska Institutet and Karolinska University Hospital Solna, Stockholm, Sweden
[11] Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
[12] Harvard―Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, Massachusetts, United States
[13] Department of Epidemiology, University Medical Center Utrecht, Utrecht, Netherlands
[14] Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands
[15] Division of Human Genetics, Genome Institute of Singapore, Singapore
[16] The Wellcome Trust Sanger Institute, Cambridge, United Kingdom
[17] Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States
[18] Department of Rheumatology, Hospital Marques de Valdecilla, Instituto de Fundación e Investigación Marques de Valdecilla, Santander, Spain
[19] Hospital Clinico San Carlos, Madrid, Spain
[20] Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
[21] Department of Rheumatology, Umea University, Umea, Sweden
[22] El Instituto de Parasitologia y Biomedicina 'López-Neyra'-Consejo Superior de Investigaciones Científicas, Avenida del Conocimiento s/n, Granada, Spain
Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate¹⁷, Wellcome Trust Case Control Consortium

Source

Nature genetics. 2012, Vol 44, Num 12, pp 1336-1340, 5 p ; ref : 17 ref

CODEN

NGENEC

ISSN

1061-4036

Scientific domain

Genetics

Publisher

Nature Publishing Group, New York, NY

Publication country

United States

Document type

Article

Language

English

Keyword (fr)

Carte génétique Chronique Densité Identification Locus Polyarthrite rhumatoïde Association génétique Immunopathologie Maladie autoimmune Pathologie du système ostéoarticulaire Rhumatisme inflammatoire

Keyword (en)

Genetic mapping Chronic Density Identification Locus Rheumatoid arthritis Immunopathology Autoimmune disease Diseases of the osteoarticular system Inflammatory joint disease

Keyword (es)

Mapa genético Crónico Densidad Identificación Locus Poliartritis reumatoidea Inmunopatología Enfermedad autoinmune Sistema osteoarticular patología Reumatismo inflamatorio

Classification

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution / 002A07C Classical genetics, quantitative genetics, hybrids / 002A07C04 Methods, theories and miscellaneous

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15D Inflammatory joint diseases

Discipline

Eukaryotes genetics. Biological and molecular evolution Osteoarticular pathology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

26701580

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS