Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
- Author
- WHITCOMB, David C1 2 3 ; LARUSCH, Jessica1 ; GUDA, Nalini M9 ; ORLICHENKO, Lidiya1 ; ALKAADE, Samer11 ; AMANN, Stephen T12 ; ANDERSON, Michelle A13 ; BAILLIE, John14 ; BANKS, Peter A15 ; CONWELL, Darwin15 ; COTE, Gregory A16 ; COTTON, Peter B17 ; KRASINSKAS, Alyssa M4 ; DISARIO, James18 ; FARRER, Lindsay A19 ; FORSMARK, Chris E20 ; JOHNSTONE, Marianne7 ; GARDNER, Timothy B21 ; GELRUD, Andres1 ; GREENHALF, William7 ; HAINES, Jonathan L22 23 ; HARTMAN, Douglas J4 ; HAWES, Robert A17 ; KLEI, Lambertus5 ; LAWRENCE, Christopher17 ; LEWIS, Michele24 ; MAYERLE, Julia8 ; MAYEUX, Richard; MELHEM, Nadine M5 ; MONEY, Mary E; MUNIRAJ, Thiruvengadam; PAPACHRISTOU, Georgios I1 ; PERICAK-VANCE, Margaret A; ROMAGNUOLO, Joseph17 ; SMITH, Jill P6 ; SCHELLENBERG, Gerard D; SHERMAN, Stuart16 ; SIMON, Peter8 ; SINGH, Vijay P1 ; SLIVKA, Adam1 ; STOLZ, Donna2 ; SUTTON, Robert7 ; ULRICH WEISS, Frank8 ; MEL WILCOX, C; ZARNESCU, Narcis Octavian1 ; BRAND, Randall E1 ; WISNIEWSKI, Stephen R; NEOPTOLEMOS, John P7 ; LERCH, Markus M8 ; TECTOR, Matt9 ; SANDHU, Bimaljit S10
[1] Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
[2] Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
[3] Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States
[4] Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
[5] Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
[6] Division of Gastroenterology and Liver Diseases, Pennsylvania State University, Hershey, Pennsylvania, United States
[7] Department of Molecular and Clinical Cancer Medicine, National Institute for Health Research Liverpool Pancreas Biomedical Research Unit, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
[8] Department of Medicine A, University Medicine Greifswald, Greifswald, Germany
[9] Aurora Health Care System, St. Luke's Medical Center, Milwaukee, Wisconsin, United States
[10] Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University Medical Center, Richmond, Virginia, United States
[11] Department of Medicine, Saint Louis University, St. Louis, Missouri, United States
[12] North Mississippi Medical Center, Tupelo, Mississippi, United States
[13] Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, United States
[14] Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States
[15] Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts, United States
[16] Department of Medicine, Indiana University Medical Center, Indianapolis, Indiana, United States
[17] Digestive Disease Center, Medical University of South Carolina, Charleston, South Carolina, United States
[18] Department of Medicine, University of Utah Health Science Center, Salt Lake City, Utah, United States
[19] Department of Medicine/ Biomedical Genetics Section, Boston University School of Medicine, Boston, Massachusetts, United States
[20] Department of Medicine, University of Florida, Gainesville, Florida, United States
[21] Department of Medicine, Division of Gastroenterology and Hepatology, Dartmouth-Hltchcock Medical Center, Hanover, New Hampshire, United States
[22] Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States
[23] Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States
[24] Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, United States - Source
Nature genetics. 2012, Vol 44, Num 12, pp 1349-1354, 6 p ; ref : 31 ref
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Alcoolisme Locus Pancréatite Risque Sporadique Variant génétique Pathologie de l'appareil digestif Pathologie du pancréas
- Keyword (en)
- Alcoholism Locus Pancreatitis Risk Sporadic Genetic variant Digestive diseases Pancreatic disease
- Keyword (es)
- Alcoholismo Locus Pancreatitis Riesgo Esporádico Variante genética Aparato digestivo patología Páncreas patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03F Alcoholism and acute alcohol poisoning
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C05 Addictive behaviors / 002B18C05B Alcoholism
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D03 Adult and adolescent clinical studies / 770-D03E Addictive behaviors / 770-D03E02 Alcoholism
- Discipline
- Eukaryotes genetics. Biological and molecular evolution Psychopathology. Psychiatry. Clinical psychology Toxicology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 26701582
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng.2466 
https://dx.doi.org/10.1038/ng.2466
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arXiv access
