A triplet combination with irinotecan (CPT-11), oxaliplatin (LOHP), continuous infusion 5-fluorouracil and leucovorin (FOLFOXIRI) plus cetuximab as first-line treatment in KRAS wt, metastatic colorectal cancer: a pilot phase II trial
- Author
- SARIDAKI, Z1 ; ANDROULAKIS, N2 ; SOUGLAKOS, J1 2 ; VARDAKIS, N2 ; VAMVAKAS, L2 ; KABOURAKI, E2 ; KALBAKIS, K2 ; HATZIDAKI, D2 ; VOUTSINA, A1 ; MAVROUDIS, D1 2 ; GEORGOULIAS, V1 2
[1] Laboratory of Tumor Cell Biology School of Medicine, University of Crete, Heraklion, Greece
[2] Department of Medical Oncology, University Hospital of Heraklion, Voutes and Stavrakia, PO BOX 1352, Heraklion, Crete 71110, Greece - Source
British journal of cancer. 2012, Vol 107, Num 12, pp 1932-1937, 6 p ; ref : 1/2 p
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- FOLFOXIRI cetuximab metastatic colorectal cancer
- Keyword (fr)
- Anticancéreux Association médicamenteuse Cancer colorectal Cancérologie Cétuximab Essai clinique phase II Fluorouracil Folinate de calcium Gène K ras Gène onc cellulaire Irinotécan Métastase Oxaliplatine Perfusion Protooncogène Stade avancé Traitement de première intention Anti-EGFR Triplés Agent alkylant Anticorps monoclonal Antimétabolite Camptothécine dérivé Cancer DNA topoisomerase Dérivé de la fluoropyrimidine Dérivé de la pyrimidine Enzyme Inhibiteur de la topoisomérase I Inhibiteur enzyme Isomerases Methyltransferases Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie du côlon Pathologie du rectum Platine II Complexe Récepteur facteur croissance épiderme Thymidylate synthase Transferases Tumeur maligne
- Keyword (en)
- Antineoplastic agent Drug combination Colorectal cancer Cancerology Cetuximab Phase II trial Fluorouracil Calcium folinate K ras Gene C-Onc gene Irinotecan Metastasis Oxaliplatin Perfusion Protooncogene Advanced stage First line treatment Triplets Alkylating agent Monoclonal antibody Antimetabolic Camptothecin derivatives Cancer DNA topoisomerase Fluoropyrimidine derivatives Pyrimidine derivatives Enzyme Topoisomerase I inhibitor Enzyme inhibitor Isomerases Methyltransferases Digestive diseases Intestinal disease Colonic disease Rectal disease Platinum II Complexes Epidermal growth factor receptor Thymidylate synthase Transferases Malignant tumor
- Keyword (es)
- Anticanceroso Asociación medicamentosa Cancer de colon y recto Cancerología Cetuximab Ensayo clínico fase II Fluorouracilo Folinato cálcico Gen K ras Gen onc celular Irinotecán Metástasis Oxaliplatino Perfusión Protooncogen Estadio avanzado Tratamiento de primera línea Agente alquilante Anticuerpo monoclonal Antimetabólito Camptothecin derivado Cáncer DNA topoisomerase Fluoropirimidina derivado Pirimidina derivado Enzima Inhibidor topoisomerase I Inhibidor enzima Isomerases Methyltransferases Aparato digestivo patología Intestino patología Colón patología Recto patología Platino II Complejo Receptor del factor de crecimiento epidérmico Thymidylate synthase Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26751668
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/bjc.2012.509 
https://dx.doi.org/10.1038/bjc.2012.509
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