Evaluation of high-resolution peripheral quantitative computed tomography, finite element analysis and biomechanical testing in a pre-clinical model of osteoporosis: A study with odanacatib treatment in the ovariectomized adult rhesus monkey
- Author
- JAYAKAR, Richa Y1 ; CABAL, Antonio2 ; MCCRACKEN, Paul J1 ; HARGREAVES, Richard5 ; HANGARTNER, Thomas N9 ; WILLIAMS, Donald S1 ; SZUMILOSKI, John3 ; SARDESAI, Swanand2 ; PHILLIPS, Eual A7 ; LAIB, Andres8 ; SCOTT, Boyd B4 ; PICKARSKI, Maureen6 ; DUONG, Le T6 ; WINKELMANN, Christopher T1
[1] Department of Imaging, Merck Research Laboratories, West Point, PA, United States
[2] Department of Modeling & Simulation, Merck Research Laboratories, West Point, PA, United States
[3] Department of Biometrics, Merck Research Laboratories, West Point, PA, United States
[4] Department of Global scientific and medical publications, Merck Research Laboratories, West Point, PA, United States
[5] Department of Neuroscience, Merck Research Laboratories, West Point, PA, United States
[6] Department of Bone Biology, Merck Research Laboratories, West Point, PA, United States
[7] School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States
[8] Scanco Medical AG, Brütisellen, Switzerland
[9] BioMedical Imaging Laboratory, Wright State University, Dayton, OH, United States - Source
Bone (New York, NY). 2012, Vol 50, Num 6, pp 1379-1388, 10 p ; ref : 38 ref
- ISSN
- 8756-3282
- Scientific domain
- Orthopedics traumatology; Physiology, morphology
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Bone microstructure FEA HR-pQCT Imaging Odanacatib
- Keyword (fr)
- Adulte Analyse quantitative Animal Elément fini Haute résolution Microstructure Modèle Morphologie Os Ostéoporose Singe Symptomatologie Tomodensitométrie Traitement Homme Imagerie médicale Mammalia Pathologie du système ostéoarticulaire Primates Radiodiagnostic Vertebrata
- Keyword (en)
- Adult Quantitative analysis Animal Finite element High resolution Microstructure Models Morphology Bone Osteoporosis Monkey Symptomatology Computerized axial tomography Treatment Human Medical imagery Mammalia Diseases of the osteoarticular system Primates Radiodiagnosis Vertebrata
- Keyword (es)
- Adulto Análisis cuantitativo Animal Elemento finito Alta resolucion Microestructura Modelo Morfología Hueso Osteoporosis Mono Sintomatología Tomodensitometría Tratamiento Hombre Imaginería médica Mammalia Sistema osteoarticular patología Primates Radiodiagnóstico Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A16 Vertebrates: anatomy and physiology, studies on body, several organs or systems
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15A Osteoporosis. Osteomalacia. Paget disease
- Discipline
- Osteoarticular pathology Vertebrates : anatomy and physiology, studies on body, several organs or systems
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 26767465
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bone.2012.03.017 
https://dx.doi.org/10.1016/j.bone.2012.03.017
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