Randomized Phase III Placebo-Controlled Trial of Letrozole Plus Oral Temsirolimus As First-Line Endocrine Therapy in Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer
- Author
- WOLFF, Antonio C1 ; LAZAR, Ann A2 ; CHAN, Arlene12 ; HACHEMI, Soulef11 ; STRAHS, Andrew13 ; CINCOTTA, Maria13 ; BERKENBLIT, Anna13 ; KRYGOWSKI, Mizue13 ; KANG, Lih Lisa13 ; MOORE, Laurence13 ; HAYES, Daniel F14 ; BONDARENKO, Igor3 ; GARIN, August M4 ; BRINCAT, Stephen5 ; CHOW, Louis6 ; YAN SUN7 ; NESKOVIC-KONSTANTINOVIC, Zora8 ; GUIMARAES, Rodrigo C9 ; FUMOLEAU, Pierre10
[1] The Johns Hopkins Kimmel Comprehensive Cancer Center, Baltimore, MD, United States
[2] University of Califomia San Francisco, San Francisco, CA, United States
[3] Municipal Clinical Hospital #4, State Medical Academy, Dnepropetrovsk, Ukraine
[4] Russian Oncological Research Center, Moscow, Russian Federation
[5] Sir Paul Boffa Hospital, Floriana, Malta
[6] UNIMED Medical Center, Wan Chai, Hong-Kong
[7] Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China
[8] Institute of Oncology and Radiology of Serbia, Belgrade, Serbia
[9] Hospital Vera Cruz, Belo Horizonte, Brazil
[10] Centre Georges-Francois Leclerc Service Oncologie, Dijon, France
[11] Pfizer, Paris, France
[12] Mount Medical Center, Perth, Australia
[13] Pfizer, Cambridge, MA, United States
[14] University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, United States - Source
Journal of clinical oncology. 2013, Vol 31, Num 2, pp 195-202, 8 p ; ref : 27 ref
- ISSN
- 0732-183X
- Scientific domain
- Medical oncology
- Publisher
- American Society of Clinical Oncology, Alexandria, VA
- Publication country
- United States
- Document type
- Article
- Language
- Russian
- Keyword (fr)
- Adulte Anticancéreux Cancer du sein Cancérologie Chimiothérapie Endocrinologie Essai clinique phase III Essai clinique Femelle Femme Glande endocrine Homme Létrozole Métastase Placebo Postménopause Stade avancé Temsirolimus Traitement de première intention Essai randomisé contrôlé Inhibiteur mTOR Stade localement avancé Antihormone Antioestrogène Cancer Composé non stéroïde Dérivé d'azole Dérivé du triazole Enzyme Estrogen synthase Inhibiteur de l'aromatase Inhibiteur enzyme Pathologie de la glande mammaire Pathologie du sein Traitement Tumeur maligne
- Keyword (en)
- Adult Antineoplastic agent Breast cancer Cancerology Chemotherapy Endocrinology Phase III trial Clinical trial Female Woman Endocrine gland Human Letrozole Metastasis Placebo Postmenopause Advanced stage Temsirolimus First line treatment Randomized controlled trial Locally advanced stage Antihormone Antiestrogen Cancer Non steroid compound Azole derivatives Triazole derivatives Enzyme Estrogen synthase Aromatase inhibitor Enzyme inhibitor Mammary gland diseases Breast disease Treatment Malignant tumor
- Keyword (es)
- Adulto Anticanceroso Cáncer del pecho Cancerología Quimioterapia Endocrinología Ensayo clínico fase III Ensayo clínico Hembra Mujer Glándula endocrina Hombre Letrozol Metástasis Placebo Postmenopausia Estadio avanzado Temsirolimus Tratamiento de primera línea Ensayo aleatorio controlado Estadio localmente avanzado Antihormona Antiestrógeno Cáncer Compuesto no esteroide Azol derivado Triazol derivado Enzima Estrogen synthase Inhibidor aromatase Inhibidor enzima Glándula mamaria patología Seno patología Tratamiento Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20E Mammary gland diseases / 002B20E02 Tumors
- Discipline
- Gynecology. Andrology. Obstetrics Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27129954
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1200/JCO.2011.38.3331 
https://dx.doi.org/10.1200/JCO.2011.38.3331
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