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Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI

Author
BELOUECHE-BABARI, M1 ; JAMIN, Y1 ; LEACH, M. O1 ; ROBINSON, S. P1 ; ARUNAN, V1 ; WALKER-SAMUEL, S1 ; REVILL, M2 ; SMITH, P. D2 ; HALLIDAY, J2 ; WATERTON, J. C2 ; BARJAT, H2 ; WORKMAN, P3
[1] Cancer Research UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, Surrey SM2 5PT, United Kingdom
[2] AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom
[3] Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom
Source

British journal of cancer. 2013, Vol 109, Num 6, pp 1562-1569, 8 p ; ref : 1 p.1/4

CODEN
BJCAAI
ISSN
0007-0920
Scientific domain
Medical oncology
Publisher
Nature Publishing Group, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
MEK biomarker diffusion-weighted MRI human tumour xenografts non-invasive imaging
Keyword (fr)
Aigu Animal Anticancéreux Cancérologie Diffusion Homme Hétérotransplantation Imagerie RMN Imagerie médicale Inhibiteur Marqueur biologique Poids Traitement Tumeur Réponse tumorale Sélumétinib Chirurgie Dérivé du benzimidazole Greffe Transplantation
Keyword (en)
Acute Animal Antineoplastic agent Cancerology Diffusion Human Heterotransplantation Nuclear magnetic resonance imaging Medical imagery Inhibitor Biological marker Weight Treatment Tumor Tumor response Selumetinib Surgery Benzimidazole derivatives Graft Transplantation
Keyword (es)
Agudo Animal Anticanceroso Cancerología Difusión Hombre Heterotrasplante Imaginería RMN Imaginería médica Inhibidor Marcador biológico Peso Tratamiento Tumor Respuesta tumoral Selumetinib Cirugía Benzimidazol derivado Injerto Trasplantación
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
27745512

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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