Human LilrB2 Is a β-Amyloid Receptor and Its Murine Homolog PirB Regulates Synaptic Plasticity in an Alzheimer's Model
- Author
- KIM, Taeho1 ; VIDAL, George S1 ; DJURISIC, Maja1 ; WILLIAM, Christopher M2 ; BIRNBAUM, Michael E3 ; CHRISTOPHER GARCIA, K3 ; HYMAN, Bradley T2 ; SHATZ, Carla J1
[1] Departments of Biology and Neurobiology and Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305, United States
[2] Neuropathology Service, Massachusetts General Hospital, Charlestown, MA 02129, United States
[3] Howard Hughes Medical Institute, Department of Molecular and Cellular Physiology, and Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, United States - Source
Science (Washington, D.C.). 2013, Vol 341, Num 6152, pp 1399-1404, 6 p
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal transgénique Démence d'Alzheimer Encéphale Extracellulaire Homme Immunoglobuline Leucocyte Modèle Plasticité synaptique Protéine amyloïde β Récepteur biologique Récepteur immunoglobuline Souris Transduction signal Récepteur RAGE Maladie dégénérative Mammalia Pathologie de l'encéphale Pathologie du système nerveux central Pathologie du système nerveux Rodentia Système nerveux central Trouble cognitif Vertebrata Voie visuelle
- Keyword (en)
- Transgenic animal Alzheimer disease Encephalon Extracellular Human Immunoglobulins Leukocyte Models Synaptic plasticity β Amyloid protein Biological receptor Immunoglobulin receptor Mouse Signal transduction RAGE receptor Degenerative disease Mammalia Cerebral disorder Central nervous system disease Nervous system diseases Rodentia Central nervous system Cognitive disorder Vertebrata Visual pathway
- Keyword (es)
- Animal transgénico Demencia Alzheimer Encéfalo Extracelular Hombre Inmunoglobulina Leucocito Modelo Plasticidad sináptica Proteína amiloide β Receptor biológico Receptor immunoglobulina Ratón Transducción señal Enfermedad degenerativa Mammalia Encéfalo patología Sistema nervosio central patología Sistema nervioso patología Rodentia Sistema nervioso central Trastorno cognitivo Vertebrata Vía visual
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25I Eye and associated structures. Visual pathways and centers. Vision
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology Vertebrates : nervous system and sense organs
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27784757
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1242077 
https://dx.doi.org/10.1126/science.1242077
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