Acute cardiac and hemodynamic effects of sildenafil on resistant hypertension
- Author
- QUINAGLIA, Thiago1 ; DE FARIA, Ana Paula C1 ; FONTANA, Vanessa1 ; BARBARO, Natália R1 ; SABBATINI, Andréa R1 ; SERTORIO, Jonas T2 ; DEMACQ, Caroline3 ; TANUS-SANTOS, José E2 ; MORENO, Heitor1
[1] Laboratory of Cardiovascular Pharmacology, Faculty of Medical Sciences and Clinic Hospital, University of Campinas (UNICAMP), FCM 10 Building, 1st Floor, Campinas, SP 13083-970, Brazil
[2] Laboratory of Cardiovascular Pharmacology, Faculty of Medicine of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil
[3] Novartis Biociências S.A., São Paulo, Brazil - Source
European journal of clinical pharmacology. 2013, Vol 69, Num 12, pp 2027-2036, 10 p ; ref : 51 ref
- ISSN
- 0031-6970
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Diastolic function Endothelial dysfunction Hemodynamic pattern Resistant hypertension Sildenafil eNOS polymorphism
- Keyword (fr)
- Aigu Coeur Génotype Homme Hypertension artérielle Hémodynamique Nitric-oxide synthase Polymorphisme Résistance Sildénafil Variabilité génétique Vasodilatateur Dysfonction endothéliale 3',5'-Cyclic-GMP phosphodiesterase Appareil circulatoire Enzyme Esterases Hydrolases Inhibiteur de la phosphodiesterase Inhibiteur de la phosphodiestérase 5 Inhibiteur enzyme Oxidoreductases Pathologie de l'appareil circulatoire Phosphoric diester hydrolases
- Keyword (en)
- Acute Heart Genotype Human Hypertension Hemodynamics Nitric-oxide synthase Polymorphism Resistance Sildenafil Genetic variability Vasodilator agent Endothelial dysfunction 3',5'-Cyclic-GMP phosphodiesterase Circulatory system Enzyme Esterases Hydrolases Phosphodiesterase inhibitor Phosphodiesterase 5 inhibitor Enzyme inhibitor Oxidoreductases Cardiovascular disease Phosphoric diester hydrolases
- Keyword (es)
- Agudo Corazón Genotipo Hombre Hipertensión arterial Hemodinámica Nitric-oxide synthase Polimorfismo Resistencia Sildenafilo Variabilidad genética Vasodilatador Disfunción del endotelio 3',5'-Cyclic-GMP phosphodiesterase Aparato circulatorio Enzima Esterases Hydrolases Inhibidor phosphodiesterase Inhibidor fosfodiesterasa 5 Inhibidor enzima Oxidoreductases Aparato circulatorio patología Phosphoric diester hydrolases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12B Blood and lymphatic vessels / 002B12B05 Arterial hypertension. Arterial hypotension
- Discipline
- Cardiology. Circulatory system General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 27933672
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00228-013-1571-z 
https://dx.doi.org/10.1007/s00228-013-1571-z
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