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MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

Author
HUIJBERS, Maartje G1 2 ; WEI ZHANG4 ; LOSEN, Mario5 ; VAN DER MAAREL, Silvère M2 ; BURDEN, Steven J4 ; VERSCHUUREN, Jan J1 ; KLOOSTER, Rinse2 ; NIKS, Erik H1 ; FRIESE, Matthew B4 ; STRAASHEIJM, Kirsten R2 ; THIJSSEN, Peter E2 ; VROLIJK, Hans3 ; PLOMP, Jaap J1 3 ; VOGELS, Pauline2
[1] Department of Neurology, Leiden University Medical Center, 2333 ZA, Leiden, Netherlands
[2] Department of Human Genetics and Leiden University Medical Center, 2333 ZA, Leiden, Netherlands
[3] Department of Molecular Cell Biology, Leiden University Medical Center, 2333 ZA, Leiden, Netherlands
[4] Molecular Neurobiology Program, Helen L. and Martin S. Kimmel Center for Biology and Medicine at the Skirball Institute, New York University Medical School, New York, NY 10016, United States
[5] Department of Neuroscience, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200 MD, Maastricht, Netherlands
Source

Proceedings of the National Academy of Sciences of the United States of America. 2013, Vol 110, Num 51, pp 20783-20788, 6 p ; ref : 54 ref

CODEN
PNASA6
ISSN
0027-8424
Scientific domain
Multidisciplinary
Publisher
National Academy of Sciences, Washington, DC
Publication country
United States
Document type
Article
Language
English
Author keyword
Dok7 Rapsyn activation loop insulin receptor neuromuscular junction
Keyword (fr)
IgG4 Insuline Jonction neuromusculaire Récepteur biologique Hormone pancréatique
Keyword (en)
IgG4 Insulin Neuromuscular junction Biological receptor Pancreatic hormone
Keyword (es)
IgG4 Insulina Unión neuromuscular Receptor biológico Hormona pancreática
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs

Discipline
Vertebrates : nervous system and sense organs
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
28024123

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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