Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial
- Author
- FUCHS, Charles S1 ; TOMASEK, Jiri2 ; MELICHAR, Bohuslav11 ; TEHFE, Mustapha12 ; TOPUZOV, Eldar13 ; ZALCBERG, John Raymond14 15 16 ; IAN CHAU17 18 ; CAMPBELL, William19 ; SIVANANDAN, Choondal20 ; PIKIEL, Joanna21 ; KOSHIJI, Minori22 ; YANZHI HSU22 ; CHO JAE YONG3 ; LIEPA, Astra M23 ; LING GAO22 ; SCHWARTZ, Jonathan D22 ; TABERNERO, Josep24 ; DUMITRU, Filip4 ; PASSALACQUA, Rodolfo5 ; GOSWAMI, Chanchal6 ; SAFRAN, Howard7 ; DOS SANTOS, Lucas Vieira8 ; APRILE, Giuseppe9 ; FERRY, David R10
[1] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States
[2] Department of Complex Oncology Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic
[3] Department of Medical Oncology, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Korea, Republic of
[4] Oncology Department, Emergency County Hospital Dr Constantin Opris, Baia Mare, Romania
[5] Medical Oncology Division, Istituti Ospitalieri di Cremona, Cremona, Italy
[6] Department of Medical Oncology, B P Poddar Hospital and Medical Research, Kolkata, West Bengal, India
[7] Department of Medicine, The Brown University Oncology Group, Brown University, Providence, RI, United States
[8] Medical Oncology Department, Gastrointestinal Oncology Division, Hospital de Câncer de Barretos and Hemomed Instituto de Oncologia e Hematologia, São Paulo, Brazil
[9] Department of Oncology, University and General Hospital, Udine, Italy
[10] Department of Medical Oncology, New Cross Hospital, West Midlands, United Kingdom
[11] Department of Oncology, Palacky University Medical School and Teaching Hospital, Olomouc, Czech Republic
[12] Department of Medical Oncology, Hôpital Notre Dame de CHUM, Montreal, Quebec, Canada
[13] State Budgetary Educational Institution of Higher Professional Education (SBEIHPE), Northwest State Medical University na II Mechnikov, Ministry of Healthcare of the Russian Federation, Russian Federation
[14] Division of Cancer Medicine, Peter McCallum Cancer Centre, East Melbourne, VIC, Australia
[15] Department of Medicine, Faculty of Medicine, University of Melbourne, Australia
[16] Department of Oncology, Faculty of Medicine, University of Melbourne, Australia
[17] Department of Medicine, Royal Marsden Hospital, London, England, United Kingdom
[18] Department of Medicine, Royal Marsden Hospital, Surrey, England, United Kingdom
[19] Department of Oncology, Hospital Herrera Llerandi-Clinicas Médicas, Guatemala
[20] Division of Cancer Research, Regional Cancer Centre, Kerala, India
[21] Wojewódzkie Centrum Onkologii Gdańsk, Poland
[22] ImClone Systems LLC, Bridgewater, NJ, United States
[23] Eli Lilly, Indianapolis, IN, United States
[24] Medical Oncology Department Vall d'Hebron University Hospital, UniversitatAutònoma de Barcelona, Barcelona, Spain
REGARD Trial Investigators - Source
Lancet (British edition). 2014, Vol 383, Num 9911, pp 31-39, 9 p ; ref : 31 ref
- CODEN
- LANCAO
- ISSN
- 0140-6736
- Scientific domain
- General medicine general surgery
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- Russian
- Keyword (fr)
- Adénocarcinome de l'estomac Adénocarcinome de l'oesophage Cancer de l'estomac Cancer de l'oesophage Essai clinique phase III Essai clinique Estomac Etude multicentrique International Jonction Médecine Placebo Randomisation Stade avancé Traitement Monothérapie Monde Appareil digestif Cancer Pathologie de l'appareil digestif Pathologie de l'estomac Pathologie de l'oesophage Tumeur maligne
- Keyword (en)
- Stomach adenocarcinoma Esophagus adenocarcinoma Stomach cancer Esophagus cancer Phase III trial Clinical trial Stomach Multicenter study International Junction Medicine Placebo Randomization Advanced stage Treatment Monotherapy World Digestive system Cancer Digestive diseases Gastric disease Esophageal disease Malignant tumor
- Keyword (es)
- Adenocarcinoma de estómago Adenocarcinoma de esófago Cáncer del estómago Cáncer del esófago Ensayo clínico fase III Ensayo clínico Estómago Estudio multicéntrico Internacional Reunión Medicina Placebo Aleatorización Estadio avanzado Tratamiento Mundo Aparato digestivo Cáncer Aparato digestivo patología Estómago patología Esófago patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13A Esophagus / 002B13A01 Tumors
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Generalities in medical sciences
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28036942
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0140-6736(13)61719-5 
https://dx.doi.org/10.1016/S0140-6736(13)61719-5
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