A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation
- Author
- OJO, Kayode K1 ; EASTMAN, Richard T2 ; KENNEDY, Mark6 ; ISOHERRANEN, Nina5 ; KIM, Laura M7 ; COMESS, Kenneth M7 ; KEMPF, Dale J7 ; VERLINDE, Christophe L. M. J4 ; SU, Xin-Zhuan2 ; KAPPE, Stefan H. I5 ; MALY, Dustin J3 ; ERKANG FAN4 ; VIDADALA, Ramasubbarao3 ; VAN VOORHIS, Wesley C1 ; ZHONGSHENG ZHANG4 ; RIVAS, Kasey L1 ; CHOI, Ryan1 ; LUTZ, Justin D5 ; REID, Molly C1 ; FOX, Anna M. W1 ; HULVERSON, Matthew A1
[1] Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, United States
[2] Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States
[3] Department of Chemistry, University of Washington, Seattle, United States
[4] Department of Biochemistry, University of Washington, Seattle, United States
[5] Department of Pharmaceutics, University of Washington, Seattle, United States
[6] Seattle Biomedical Research Institute, Washington, United States
[7] Global Pharmaceutical R&D, AbbVie, North Chicago, Illinois, United States - Source
The Journal of infectious diseases. 2014, Vol 209, Num 2, pp 275-284, 10 p ; ref : 29 ref
- CODEN
- JIDIAQ
- ISSN
- 0022-1899
- Scientific domain
- Immunology, immunopathology, allergology; Microbiology, infectious diseases; Tropical medicine
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Génétique Infection Paludisme Transmission Parasitose Protozoose
- Keyword (en)
- Genetics Infection Malaria Transmission Parasitosis Protozoal disease
- Keyword (es)
- Genética Infección Paludismo Transmisión Parasitosis Protozoosis
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05E Parasitic diseases / 002B05E02 Protozoal diseases / 002B05E02B Human protozoal diseases / 002B05E02B4 Malaria
- Discipline
- Infectious pathology Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28319680
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/infdis/jit522 
https://dx.doi.org/10.1093/infdis/jit522
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