LINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk
- Author
- TAJUDDIN, S. M1 ; AMARAL, A. F. S1 ; MARQUEZ, M1 ; URDINGUIO, R. G2 ; GARCIA-CLOSAS, R10 ; ROTHMAN, N3 ; KOGEVINAS, M11 ; REAL, F. X12 13 ; FRAGA, M. F14 2 ; MALATS, N1 ; FERNANDEZ, A. F2 ; CHANOCK, S3 ; SILVERMAN, D. T3 ; TARDON, A4 5 ; CARRATO, A6 7 ; GARCIA-CLOSAS, M8 ; JACKSON, B. P9 ; TORANO, E. G2
[1] Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain
[2] Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Asturias 33006, Spain
[3] Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-7335, United States
[4] Molecular Epidemiology Group, Instituto Universitario de Oncologia, Universidad de Oviedo, Oviedo, Asturias 33006, Spain
[5] CIBERESP, Barcelona, Spain
[6] Molecular Oncology Group, Hospital General Universitario de Elche, Elche, Alicante 03203, Spain
[7] Department of Medical Oncology, Hospital Ramon y Cajal, Madrid 28034, Spain
[8] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom
[9] Trace Element Analysis Core, Department of Earth Sciences, Dartmouth College, Hanover, NH 03755, United States
[10] Unidad de Investigación, Hospital Universitario de Canarias, La Laguna 38320, Spain
[11] Centre for Research in Environmental Epidemiology (CREAL), Barcelona 08003, Spain
[12] Epithelial Carcinogenesis Group, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain
[13] Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08002, Spain
[14] Department of Immunology and Oncology, Centro Nacional de Biotecnología/CNB-CSIC, Cantoblanco, Madrid 28049, Spain
Spanish Bladder Cancer/EPICURO Study investigators, Spain - Source
British journal of cancer. 2014, Vol 110, Num 8, pp 2123-2130, 8 p ; ref : 1 p.1/4
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- DNA methylation LINE-1 repetitive sequences bladder cancer epigenetic-gene interaction one-carbon metabolism
- Keyword (fr)
- Cancer de la vessie Cancérologie Carbone Epigénétique Facteur risque Génotype Interaction génique Leucocyte Métabolisme Méthylation Phosphatidylethanolamine N-methyltransferase Risque Séquence répétée Variabilité génétique Variant DNA methyltransferase Cancer Enzyme Methyltransferases Pathologie de l'appareil urinaire Pathologie de la vessie Pathologie des voies urinaires Transferases Tumeur maligne
- Keyword (en)
- Bladder cancer Cancerology Carbon Epigenetics Risk factor Genotype Gene interaction Leukocyte Metabolism Methylation Phosphatidylethanolamine N-methyltransferase Risk Repeated sequence Genetic variability Variant Cancer Enzyme Methyltransferases Urinary system disease Bladder disease Urinary tract disease Transferases Malignant tumor
- Keyword (es)
- Cáncer de la vejiga Cancerología Carbono Epigenética Factor riesgo Genotipo Interacción génica Leucocito Metabolismo Metilación Phosphatidylethanolamine N-methyltransferase Riesgo Secuencia repetida Variabilidad genética Variante Cáncer Enzima Methyltransferases Aparato urinario patología Vejiga patología Vía urinaria patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14D Tumors of the urinary system / 002B14D02 Urinary tract. Prostate gland
- Discipline
- Nephrology. Urinary tract diseases Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28399879
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/bjc.2014.67 
https://dx.doi.org/10.1038/bjc.2014.67
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