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A phase 1 and dose-finding study of LY2523355 (litronesib), an Eg5 inhibitor, in Japanese patients with advanced solid tumors

Author
WAKUI, Hiroshi1 ; YAMAMOTO, Noboru1 ; AKINAGA, Shiro3 ; TAMURA, Tomohide1 ; KITAZONO, Satoru1 ; MIZUGAKI, Hidenori1 ; NAKAMICHI, Shinji1 ; FUJIWARA, Yutaka1 ; NOKIHARA, Hiroshi1 ; YAMADA, Yasuhide2 ; SUZUKI, Kohei3 ; KANDA, Hironori3
[1] Department of Thoracic Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku. Tokyo 104-0045, Japan
[2] Department of Gastrointestinal Oncology, National Cancer Center Hospital. 5-1- 1. Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
[3] Development Division. Kyowa Hakko Kirin Co., Ltd, 1-6- 1, Ohtemachi, Chiyoda-ku. Tokyo 100-8185, Japan
Source

Cancer chemotherapy and pharmacology. 2014, Vol 74, Num 1, pp 15-23, 9 p ; ref : 32 ref

CODEN
CCPHDZ
ISSN
0344-5704
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
Springer, Heidelberg
Publication country
Germany
Document type
Article
Language
English
Author keyword
Eg5 inhibitor LY2523355 Litronesib Phase 1 study Solid tumor
Keyword (fr)
Anticancéreux Dose Essai clinique phase I Homme Stade avancé Tumeur solide Inhibiteur de KSP Litronésib Japon Cancer Tumeur maligne Asie
Keyword (en)
Antineoplastic agent Dose Phase I trial Human Advanced stage Solid tumor Litronesib Japan Cancer Malignant tumor Asia
Keyword (es)
Anticanceroso Dosis Ensayo clínico fase I Hombre Estadio avanzado Tumor sólido Litronesib Japón Cáncer Tumor maligno Asia
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)

Discipline
Pharmacological treatments Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
28573035

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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