Leptin resistance and obesity in mice with deletion of methyl-CpG-binding protein 2 (MeCP2) in hypothalamic pro-opiomelanocortin (POMC) neurons
- Author
- XIAORUI WANG1 2 ; LACZA, Zsombor3 ; SUN, Yi E4 ; WEIPING HAN2 5 6
[1] Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), No. 02-02 Helios, 11 Biopolis Way, Singapore 138667, Singapore
[2] Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
[3] Department of Human Physiology and Clinical Experimental Research, Semmelweis University, Budapest, Hungary
[4] Department of Molecular and Medical Pharmacology, University of California Los Angeles (UCLA), Los Angeles, CA, United States
[5] Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore
[6] Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore - Source
Diabetologia (Berlin). 2014, Vol 57, Num 1, pp 236-245, 10 p ; ref : 49 ref
- ISSN
- 0012-186X
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Energy homeostasis Epigenetic Leptin resistance NA methylation Obesity Rett syndrome
- Keyword (fr)
- Animal Diabète Délétion Epigénétique Etat nutritionnel Homéostasie Hypothalamus Leptine Méthylation Neurone Obésité Proopiocortine Protéine liaison Résistance tissu cible Souris Syndrome de Rett Adipokine Encéphale Endocrinopathie Maladie dégénérative Maladie héréditaire Mammalia Pathologie de l'encéphale Pathologie du système nerveux central Pathologie du système nerveux Prohormone Rodentia Système nerveux central Trouble de la nutrition Vertebrata
- Keyword (en)
- Animal Diabetes mellitus Deletion Epigenetics Nutritional status Homeostasis Hypothalamus Leptin Methylation Neuron Obesity Proopiocortin Binding protein Target tissue resistance Mouse Rett syndrome Adipokine Encephalon Endocrinopathy Degenerative disease Genetic disease Mammalia Cerebral disorder Central nervous system disease Nervous system diseases Prohormone Rodentia Central nervous system Nutrition disorder Vertebrata
- Keyword (es)
- Animal Diabetes Deleción Epigenética Estado nutricional Homeostasis Hipotálamo Leptina Metilación Neurona Obesidad Proopiocortina Proteína enlace Resistencia tejido blanco Ratón Rett síndrome Adipoquina Encéfalo Endocrinopatía Enfermedad degenerativa Enfermedad hereditaria Mammalia Encéfalo patología Sistema nervosio central patología Sistema nervioso patología Prohormona Rodentia Sistema nervioso central Trastorno nutricíon Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity
- Discipline
- Endocrinopathies Metabolic diseases Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28594639
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00125-013-3072-0 
https://dx.doi.org/10.1007/s00125-013-3072-0
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