TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass
- Author
- TAKAMOTO, Iseki1 2 3 ; KUBOTA, Naoto1 2 3 4 ; SAKURAI, Yoshitaka1 ; IWAMOTO, Masahiko1 ; KITAMURA, Tadahiro7 ; UEKI, Kohjiro1 2 3 ; KADOWAKI, Takashi1 2 ; NAKAYA, Keizo1 ; KUMAGAI, Katsuyoshi1 5 ; HASHIMOTO, Shinji1 ; KUBOTA, Tetsuya1 3 4 6 ; INOUE, Mariko1 ; KAJIWARA, Eiji1 ; KATSUYAMA, Hisayuki1 ; OBATA, Atsushi1
[1] Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
[2] Translational Systems Biology and Medicine Initiative (TSBMI), The University of Tokyo, Tokyo, Japan
[3] Division of Applied Nutrition, National Institute of Health and Nutrition, Tokyo, Japan
[4] Laboratory for Metabolic Homeostasis, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan
[5] Laboratory Animal Research Center, Tokyo Medical University, Tokyo, Japan
[6] Division of Cardiovascular Medicine, Toho University, Ohashi Hospital, Tokyo, Japan
[7] Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma, Japan - Source
Diabetologia (Berlin). 2014, Vol 57, Num 3, pp 542-553, 12 p ; ref : 50 ref
- ISSN
- 0012-186X
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Beta cell proliferation Dominant-negative form Insulin production Insulin secretion TCF7L2 Wnt/β-catenin signalling
- Keyword (fr)
- Animal Caténine Cellule β Diabète Glucose Homéostasie Insuline Multiplication cellulaire Souris Sécrétion Endocrinopathie Hormone pancréatique Ilot Langerhans Mammalia Pancréas endocrine Rodentia Vertebrata
- Keyword (en)
- Animal Catenin β Cell Diabetes mellitus Glucose Homeostasis Insulin Cell proliferation Mouse Secretion Endocrinopathy Pancreatic hormone Langerhans islet Mammalia Endocrine pancreas Rodentia Vertebrata
- Keyword (es)
- Animal Catenina Célula β Diabetes Glucosa Homeostasis Insulina Multiplicación celular Ratón Secreción Endocrinopatía Hormona pancreática Isla Langerhans Mammalia Páncreas endocrino Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Discipline
- Endocrinopathies
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28594653
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00125-013-3131-6 
https://dx.doi.org/10.1007/s00125-013-3131-6
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