Breast-Cancer Risk in Families with Mutations in PALB2

Author

ANTONIOU, A. C¹ ; CASADEI, S⁷ ; TOMIAK, E¹⁶ ; NEUHAUSEN, S. L¹⁹ ; TEO, Z. L²¹ ; KHAN, S⁸ ; AITTOMÄKI, K⁹ ; MOILANEN, J. S¹¹ ; TURNBULL, C⁶ ; SEAL, S⁶ ; MANNERMAA, A¹² ; KALLIONIEMI, A¹³ ; HEIKKINEN, T⁸ ; LINDEMAN, G. J^{22 23} ; BUYS, S. S; ANDRULIS, I. L¹⁷ ; RADICE, P; TONDINI, C; MANOUKIAN, S; TOLAND, A. E; MIRON, P; WEITZEL, J. N²⁰ ; DOMCHEK, S. M; BARROWDALE, D¹ ; POPPE, B¹⁴ ; CLAES, K. B. M¹⁴ ; YANNOUKAKOS, D¹⁵ ; CONCANNON, P; BERNSTEIN, J. L; JAMES, P. A²⁴ ; EASTON, D. F^{1 2 3} ; GOLDGAR, D. E; HOPPER, J. L²⁵ ; RAHMAN, N⁶ ; PYLKÄS, K¹⁰ ; PETERLONGO, P; NEVANLINNA, H⁸ ; KING, M.-C⁷ ; COUCH, F. J; SOUTHEY, M. C²¹ ; WINQVIST, R¹⁰ ; FOULKES, W. D¹⁸ ; TISCHKOWITZ, M^{4 5} ; ROBERTS, J⁵ ; LEE, A¹ ; SUBRAMANIAN, D⁵ ; DE LEENEER, K¹⁴ ; FOSTIRA, F¹⁵
[1] Department of Public Health and Primary Care, University of Cambridge, United Kingdom
[2] Department of Oncology, University of Cambridge, United Kingdom
[3] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, United Kingdom
[4] Department of Medical Genetics and National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, United Kingdom
[5] Department of Clinical Genetics, East Anglian Regional Genetics Service, Addenbrooke's Hospital, Cambridge, United Kingdom
[6] Oncogenetics Team, Institute of Cancer Research and Royal Marsden National Health Service Foundation Trust, London, United Kingdom
[7] Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, United States
[8] Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
[9] Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland
[10] Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, and the Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Center NordLab, Oulu University Hospital, Finland
[11] Department of Clinical Genetics, University of Oulu and Oulu University Hospital, Oulu, Finland
[12] Biocenter Kuopio and Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland
[13] Institute of Biomedical Technology-Cancer Genomics, University of Tampere, Tampere, Finland
[14] Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium
[15] Molecular Diagnostics Laboratory, Institute of Nuclear and Radiologic Sciences and Technology, Energy and Safety, National Center for Scientific Research Demokritos, Athens, Greece
[16] Department of Genetics, Eastern Ontario Regional Genetics Program, Children's Hospital of Eastern Ontario, Ottawa, Canada
[17] Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
[18] Program in Cancer Genetics, Departments of Human Genetics and Oncology, Lady Davis Institute, and Research Institute, McGill University Health Centre, McGill University, Montreal, Canada
[19] Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, United States
[20] Division of Clinical Cancer Genetics, City of Hope, Duarte, CA, United States
[21] Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia
[22] Familial Cancer Centre, Royal Melbourne Hospital, Parkville, Australia
[23] Stem Cells and Cancer Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia
[24] Familial Cancer Centre, Peter Mac-Callum Cancer Centre, Melbourne, Australia
[25] Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Melbourne, Australia

Source

The New England journal of medicine. 2014, Vol 371, Num 6, pp 497-506, 10 p ; ref : 38 ref

CODEN

NEJMAG

ISSN

0028-4793

Scientific domain

General medicine general surgery

Publisher

Massachusetts Medical Society, Waltham, MA

Publication country

United States

Document type

Article

Language

English

Keyword (fr)

Cancer du sein Etude familiale Facteur risque Mutation Médecine Cancer Pathologie de la glande mammaire Pathologie du sein Tumeur maligne

Keyword (en)

Breast cancer Family study Risk factor Mutation Medicine Cancer Mammary gland diseases Breast disease Malignant tumor

Keyword (es)

Cáncer del pecho Estudio familiar Factor riesgo Mutación Medicina Cáncer Glándula mamaria patología Seno patología Tumor maligno

Classification

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B01 General aspects

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20E Mammary gland diseases / 002B20E02 Tumors

Discipline

Generalities in medical sciences Gynecology. Andrology. Obstetrics Tumours

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

28722119

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS