Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle
- Author
- DE MATTOS-ARRUDA, L1 2 3 ; WEIGELT, B3 ; PISCUOGLIO, S3 ; OLIVEIRA, M1 ; SMOLDERS, Y3 ; PATEL, P6 ; NORTON, L7 ; TABERNERO, J1 2 ; BERGER, M. F3 ; SEOANE, J1 2 8 ; RIEIS, J. S3 ; CORTES, J1 ; WON, H. H3 ; NG, C. K. Y3 ; NUCIFORO, P1 ; BIDARD, F.-C3 4 ; AURA, C1 ; SAURA, C1 ; PEG, V5
[1] Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Barcelona, Spain
[2] Universitat Autònoma de Barcelona, Barcelona, Spain
[3] Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, United States
[4] Department of Medical Oncology, Institut Curie, Paris, France
[5] Department of Pathology, Vall d'Hebron University Hospital, Barcelona, Spain
[6] Genentech, Inc., San Francisco, United States
[7] Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, United States
[8] Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain - Source
Annals of oncology. 2014, Vol 25, Num 9, pp 1729-1735, 7 p ; ref : 31 ref
- ISSN
- 0923-7534
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- breast cancer cell-free tumor DNA disease monitoring intra-tumor heterogeneity massively parallel sequencing
- Keyword (fr)
- Cancer du sein Cellule tumorale DNA De novo Génétique Hétérogénéité Mutation Surveillance Système acellulaire Séquençage Tumeur maligne Cellule tumorale circulante Cancer Pathologie de la glande mammaire Pathologie du sein
- Keyword (en)
- Breast cancer Tumor cell DNA De novo Genetics Heterogeneity Mutation Surveillance Cell free system Sequencing Malignant tumor Cancer Mammary gland diseases Breast disease
- Keyword (es)
- Cáncer del pecho Célula tumoral DNA De novo Genética Heterogeneidad Mutación Vigilancia Sistema acelular Sequencing Tumor maligno Cáncer Glándula mamaria patología Seno patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20E Mammary gland diseases / 002B20E02 Tumors
- Discipline
- Gynecology. Andrology. Obstetrics Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28752608
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/annonc/mdu239 
https://dx.doi.org/10.1093/annonc/mdu239
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