Asymmetrical Polymer Vesicles with a Stealthy Outer Corona and an Endosomal-Escape-Accelerating Inner Corona for Efficient Intracellular Anticancer Drug Delivery
- Author
- QIUMING LIU1 ; JING CHEN1 ; JIANZHONG DU1
[1] School of Materials Science and Engineering, Key Laboratory of Advanced Civil Engineering Materials of Ministry of Education, Tongji University, 4800 Caoan Road, Shanghai, 201804, China - Source
Biomacromolecules. 2014, Vol 15, Num 8, pp 3072-3082, 11 p ; ref : 54 ref
- ISSN
- 1525-7797
- Scientific domain
- Biochemistry, molecular biology, biophysics; Polymers, paint and wood industries
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acrylique acide copolymère Activité biologique Agrégation moléculaire Anticancéreux Caprolactone copolymère Cellule tumorale Cinétique Copolymère biséquencé Cytotoxicité Doxorubicine Endocytose Espace intracellulaire Ethylène oxyde copolymère Etude expérimentale Internalisation Ionomère Lactone copolymère Libération Nanoencapsulation Polymère amphiphile Polymère monodispersé Polymère vecteur Polymérisation ouverture cycle Polymérisation transfert atome Potentiel électrocinétique Pouvoir tampon Préparation Solution aqueuse Terpolymère Vecteur médicament Vésicule pH Echappement endosomal Propriété biologique
- Keyword (en)
- Acrylic acid copolymer Biological activity Molecular aggregation Antineoplastic agent Caprolactone copolymer Tumor cell Kinetics Diblock copolymer Cytotoxicity Doxorubicin Endocytosis Intracellular space Ethylene oxide copolymer Experimental study Internalization Ionomer Lactone copolymer Release Nanoencapsulation Amphiphilic polymer Monodispersed polymer Control release polymer Ring opening polymerization Atom transfer polymerization Electrokinetic potential Buffering capacity Preparation Aqueous solution Terpolymer Drug carrier Vesicle pH Biological properties
- Keyword (es)
- Acrílico ácido copolímero Actividad biológica Agregación molecular Anticanceroso Caprolactona copolímero Célula tumoral Cinética Copolímero bisecuencia Citotoxicidad Doxorubicina Endocitosis Espacio intracelular Etileno óxido copolímero Estudio experimental Internalización Ionómero Lactona copolímero Liberación Nanoencapsulación Polímero amfifilo Polímero monodispersado Polímero vector Polimerización abertura ciclo Polimerización transferencia atomo Potencial electrocinético Poder tampón Preparación Solución acuosa Terpolímero Vector medicamento Vesícula pH Propiedad biológica
- Classification
- Pascal
- 001 Exact sciences and technology / 001D Applied sciences / 001D09 Physicochemistry of polymers / 001D09D Organic polymers / 001D09D04 Properties and characterization / 001D09D04I Special properties (catalyst, reagent or carrier)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology Physical chemistry of polymers
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28765496
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/bm500676e 
https://dx.doi.org/10.1021/bm500676e
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