Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation
- Author
- SOUCHEK, J. J1 ; BAINE, M. J1 ; LAZENBY, A6 ; JOHANSSON, S. L6 ; JAIN, M1 3 ; BATRA, S. K1 3 ; LIN, C2 ; RACHAGANI, S3 ; GUPTA, S3 ; KAUR, S3 ; LESTER, K3 ; ZHENG, D2 ; CHEN, S4 ; SMITH, L5
[1] Fred & Pamela Buffet Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, United States
[2] Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, United States
[3] Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, United States
[4] Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, United States
[5] Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, United States
[6] Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, United States - Source
British journal of cancer. 2014, Vol 111, Num 6, pp 1139-1149, 11 p ; ref : 1 p.3/4
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- cholesterol pancreatic cancer radiation resistance radiosensitiser zoledronic acid
- Keyword (fr)
- Acide zolédronique Anticancéreux Antiostéoporotique Antirésorptif Biosynthèse Cancer du pancréas Cancérologie Cholestérol Ciblage Radiosensibilisant Résistance rayonnement Bisphosphonates Cancer Dérivé de l'acide diphosphonique Lipide Pathologie de l'appareil digestif Pathologie du pancréas Tumeur maligne
- Keyword (en)
- Zoledronic acid Antineoplastic agent Antiosteoporotic Antiresorptive agent Biosynthesis Pancreas cancer Cancerology Cholesterol Targeting Radiosensitizing agent Radiation resistance Bisphosphonates Cancer Diphosphonic acid derivatives Lipids Digestive diseases Pancreatic disease Malignant tumor
- Keyword (es)
- Acido zoledrónico Anticanceroso Antiosteoporótico Antirresortivo Biosíntesis Cáncer del páncreas Cancerología Colesterol Blancado Radiosensibilizante Resistencia radiación Bisfosfonatos Cáncer Difosfonico ácido derivado Lípido Aparato digestivo patología Páncreas patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28831210
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/bjc.2014.385 
https://dx.doi.org/10.1038/bjc.2014.385
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