Targeting DNA repair with combination veliparib (ABT-888) and temozolomide in patients with metastatic castration-resistant prostate cancer
- Author
- HUSSAIN, Maha1 ; CARDUCCI, Michael A2 ; ALUMKAL, Joshi J6 ; SLOVIN, Susan3 ; CETNAR, Jeremy4 ; JIANG QIAN5 ; MCKEEGAN, Evelyn M5 ; REFICI-BUHR, Marion5 ; CHYLA, Brenda5 ; SHEPHERD, Stacie P5 ; GIRANDA, Vincent L5
[1] Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, United States
[2] Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, United States
[3] Genitourinary Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY, United States
[4] Department of Medicine, Carbone Cancer Center, University of Wisconsin, Madison, WI, United States
[5] AbbVie Inc, North Chicago, IL, United States
[6] Knight Cancer Institute, Oregon Health & Science University, Portland, OR, United States - Source
Investigational new drugs. 2014, Vol 32, Num 5, pp 904-912, 9 p ; ref : 41 ref
- CODEN
- INNDDK
- ISSN
- 0167-6997
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Springer, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Combination therapy Metastatic castration-resistantprostate cancer Pilot study Temozolomide Veliparib
- Keyword (fr)
- Anticancéreux Cancer de la prostate Castration Ciblage Cible DNA Homme Métastase Résistance Stade avancé Traitement associé Tumeur maligne Témozolomide Réparation DNA Véliparib Agent alkylant Cancer Dérivé du benzimidazole Pathologie de l'appareil génital mâle Pathologie de l'appareil urinaire Pathologie de la prostate
- Keyword (en)
- Antineoplastic agent Prostate cancer Castration Targeting Target DNA Human Metastasis Resistance Advanced stage Combined treatment Malignant tumor Temozolomide DNA repair Veliparib Alkylating agent Cancer Benzimidazole derivatives Male genital diseases Urinary system disease Prostate disease
- Keyword (es)
- Anticanceroso Cáncer de la próstata Castración Blancado Blanco DNA Hombre Metástasis Resistencia Estadio avanzado Tratamiento asociado Tumor maligno Temozolomida Veliparib Agente alquilante Cáncer Benzimidazol derivado Aparato genital macho patología Aparato urinario patología Prostata patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14D Tumors of the urinary system / 002B14D02 Urinary tract. Prostate gland
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20B Male genital diseases / 002B20B02 Tumors
- Discipline
- Gynecology. Andrology. Obstetrics Nephrology. Urinary tract diseases Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 28891048
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s10637-014-0099-0 
https://dx.doi.org/10.1007/s10637-014-0099-0
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